Enhanced cyclooxygenase-2 expression levels and metalloproteinase 2 and 9 activation by Hexachlorobenzene in human endometrial stromal cells
F Chiappini, JI Bastón, A Vaccarezza, JJ Singla… - Biochemical …, 2016 - Elsevier
Hexachlorobenzene (HCB) is an organochlorine pesticide that induces toxic reproductive
effects in laboratory animals. It is a dioxin-like compound and a weak ligand of the aryl …
effects in laboratory animals. It is a dioxin-like compound and a weak ligand of the aryl …
Endocrine disruptor hexachlorobenzene induces cell migration and invasion, and enhances aromatase expression levels in human endometrial stromal cells
F Chiappini, L Ceballos, C Olivares, JI Baston… - Food and Chemical …, 2022 - Elsevier
Endometriosis is the presence and growth of endometrial tissue outside of the uterus.
Previous studies have suggested that endocrine disrupting chemicals such as …
Previous studies have suggested that endocrine disrupting chemicals such as …
Exposure to environmental concentrations of hexachlorobenzene induces alterations associated with endometriosis progression in a rat model
F Chiappini, M Sánchez, N Miret, C Cocca… - Food and Chemical …, 2019 - Elsevier
Hexachlorobenzene (HCB) is a dioxin-like compound widely distributed and is a weak
ligand of the aryl hydrocarbon receptor (AhR). Endometriosis is a disease characterized by …
ligand of the aryl hydrocarbon receptor (AhR). Endometriosis is a disease characterized by …
Dioxin-like rather than non-dioxin-like PCBs promote the development of endometriosis through stimulation of endocrine–inflammation interactions
Polychlorinated biphenyls (PCBs) contain 209 congeners with various structure–activities.
Exposure to PCBs was related to disorders of female reproduction. Endometriosis (EM) is an …
Exposure to PCBs was related to disorders of female reproduction. Endometriosis (EM) is an …
Combination of estrogen and dioxin is involved in the pathogenesis of endometriosis by promoting chemokine secretion and invasion of endometrial stromal cells
J Yu, Y Wang, WH Zhou, L Wang, YY He… - Human …, 2008 - academic.oup.com
BACKGROUND The CC chemokines, regulated on activation, normal T-cell expressed and
secreted (RANTES) and macrophage-inflammatory protein-1alpha (MIP-1α), have been …
secreted (RANTES) and macrophage-inflammatory protein-1alpha (MIP-1α), have been …
Polychlorinated biphenyl 104 promotes migration of endometrial stromal cells in endometriosis
T Hu, M Yao, X Fu, C Chen, R Wu - Toxicology Letters, 2018 - Elsevier
Polychlorinated biphenyls (PCBs), as part of environmental contaminants, have been
proved to be related to endometriosis. This study is to investigate the effect of PCB 104 on …
proved to be related to endometriosis. This study is to investigate the effect of PCB 104 on …
Histomorphometric alteration and cell-type specific modulation of arylhydrocarbon receptor and estrogen receptor expression by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin …
M Kitajima, KN Khan, A Fujishita, H Masuzaki… - Reproductive …, 2004 - Elsevier
Our purpose was to examine the effect of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD),
either singly (10μg/kg) or with 17β-estradiol (E2, 100μg/kg), on the growth of endometriosis …
either singly (10μg/kg) or with 17β-estradiol (E2, 100μg/kg), on the growth of endometriosis …
The potential role of environmental toxins in the pathophysiology of endometriosis
KL Bruner-Tran, SE Rier, E Eisenberg… - Gynecologic and …, 1999 - karger.com
Environmental contaminants that are known to disrupt steroid action can influence the
development of reproductive diseases. Our group has focused on whether 2, 3, 7, 8 …
development of reproductive diseases. Our group has focused on whether 2, 3, 7, 8 …
Endocrine disruptors and endometriosis
Endometriosis is a hormone-dependent inflammatory gynecological disease of reproductive-
age women. It is clinically and pathologically characterized by the presence of functional …
age women. It is clinically and pathologically characterized by the presence of functional …
Hexachlorobenzene promotes angiogenesis in vivo, in a breast cancer model and neovasculogenesis in vitro, in the human microvascular endothelial cell line HMEC …
C Pontillo, A Español, F Chiappini, N Miret, C Cocca… - Toxicology letters, 2015 - Elsevier
Exposure to environmental pollutants may alter proangiogenic ability and promotes tumor
growth. Hexachlorobenzene (HCB) is an organochlorine pesticide found in maternal milk …
growth. Hexachlorobenzene (HCB) is an organochlorine pesticide found in maternal milk …