Humans detect skin temperature changes that are perceived as warm or cool. Like humans,
mice report forepaw skin warming with perceptual thresholds of less than 1° C and do not …

The temperature of an object provides important somatosensory information for animals
performing tactile tasks. Humans can perceive skin cooling of less than one degree, but the …

Perception of the thermal environment begins with the activation of peripheral
thermosensory neurons innervating the body surface. To understand how temperature is …

We have shown that cutaneous cooling-sensitive receptors can work as thermostats of skin
temperature against cooling. However, molecule of the thermostat is not known. Here, we …

Undoubtedly, adjusting our thermoregulatory behavior represents the most effective
mechanism to maintain thermal homeostasis and ensure survival in the diverse thermal …

The abilities to sense environmental and internal temperatures are required for survival,
both for maintenance of homeostasis and for avoidance of tissue-damaging noxious …

Temperature transduction in mammals is possible because of the presence of a set of
temperature-dependent transient receptor potential (TRP) channels in dorsal root ganglia …

Afferent neural transmission of temperature sensation from skin thermoreceptors to the
central thermoregulatory system is important for the defense of body temperature against …

Environmental temperature is thought to be directly sensed by neurons through their
projections in the skin. A subset of the mammalian transient receptor potential (TRP) family …

Mammalian somatosenory neurons respond to thermal stimuli and allow animals to reliably
discriminate hot from cold and to select their preferred environments. Previously, we …