[HTML][HTML] Effect of spermidine on ameliorating spermatogenic disorders in diabetic mice via regulating glycolysis pathway
JY Wang, D Ma, M Luo, YP Tan, O Zhong… - Reproductive Biology …, 2022 - Springer
Diabetes mellitus (DM), a high incidence metabolic disease, is related to the impairment of
male spermatogenic function. Spermidine (SPM), one of the biogenic amines, was identified …
male spermatogenic function. Spermidine (SPM), one of the biogenic amines, was identified …
Metformin ameliorates testicular damage in male mice with streptozotocin‐induced type 1 diabetes through the PK2/PKR pathway
Y Liu, Z Yang, D Kong, Y Zhang… - Oxidative medicine and …, 2019 - Wiley Online Library
Approximately 90% of male diabetes mellitus patients have varying degrees of testicular
dysfunction. The molecular mechanism underlying diabetes‐induced testicular damage has …
dysfunction. The molecular mechanism underlying diabetes‐induced testicular damage has …
Effects of experimental diabetes on testis proliferations and apoptosis in rats
This work aimed to investigate the role of diabetes on cell proliferation, and apoptosis in
testis. The rats were randomly allotted into one of two experimental groups: control and …
testis. The rats were randomly allotted into one of two experimental groups: control and …
[HTML][HTML] Testicular histopathology and phosphorylated protein changes in mice with diabetes induced by multiple-low doses of streptozotocin: An experimental study
A Sampannang, S Arun, J Burawat… - International Journal …, 2018 - ncbi.nlm.nih.gov
Background: The streptozotocin (STZ)-induced diabetic model is widely used to evaluate the
adverse effects of diabetes mellitus (DM) on spermatogenesis and testicular …
adverse effects of diabetes mellitus (DM) on spermatogenesis and testicular …
[HTML][HTML] Nicotinamide mononucleotide improves spermatogenic function in streptozotocin-induced diabetic mice via modulating the glycolysis pathway: Nicotinamide …
D Ma, L Hu, J Wang, M Luo, A Liang, X Lei… - Acta Biochimica et …, 2022 - ncbi.nlm.nih.gov
Spermatogenic dysfunction is one of the major secondary complications of diabetes;
however, the underlying mechanisms remain ill-defined, and there is no available drug or …
however, the underlying mechanisms remain ill-defined, and there is no available drug or …
Studies on the mechanism of testicular dysfunction in the early stage of a streptozotocin induced diabetic rat model
Streptozotocin (STZ) induced diabetic model has been widely used to study the effects of
diabetes mellitus (DM) on male infertility, but it remains unclear whether the responses in …
diabetes mellitus (DM) on male infertility, but it remains unclear whether the responses in …
[HTML][HTML] Hyperglycemia induces spermatogenic disruption via major pathways of diabetes pathogenesis
CC Maresch, DC Stute, T Fleming, J Lin… - Scientific Reports, 2019 - nature.com
Diabetes-induced hyperglycemia has previously been shown to impact on male sub-
/infertility, however, still little is known about the underlying mechanisms. In the present study …
/infertility, however, still little is known about the underlying mechanisms. In the present study …
The effect of streptozotocin induced diabetes on sperm function: a closer look at AGEs, RAGEs, MAPKs and activation of the apoptotic pathway
TS Omolaoye, SS Du Plessis - Toxicological Research, 2021 - Springer
This study was designed to (1) investigate the possible mechanisms through which diabetes-
induced advanced glycation end products (AGEs) and receptor for AGEs (RAGE) activation …
induced advanced glycation end products (AGEs) and receptor for AGEs (RAGE) activation …
Myristic acid defends against testicular oxidative stress, inflammation, apoptosis: Restoration of spermatogenesis, steroidogenesis in diabetic rats
ASM Khalil, N Giribabu, S Yelumalai, H Shahzad… - Life sciences, 2021 - Elsevier
Diabetes mellitus (DM) may lead to testicular-related infertility while Myristic acid (MA) is
beneficial to lower hyperglycaemia. Thus, we hypothesized that MA could protect testes …
beneficial to lower hyperglycaemia. Thus, we hypothesized that MA could protect testes …
Gynura procumbens Improved Fertility of Diabetic Rats: Preliminary Study of Sperm Proteomic
KA Kamaruzaman, WM Aizat… - … and Alternative Medicine, 2018 - Wiley Online Library
Gynura procumbens (GP) is a medicinal herb that has long been known as anti‐
inflammatory and antihyperglycaemic. Recently, this herbal extract has been associated with …
inflammatory and antihyperglycaemic. Recently, this herbal extract has been associated with …
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