The treatment of large craniofacial bone defects requires more advanced and effective
strategies than bone grafts since such defects are challenging and cannot heal without …

Abstract 3D printed bioactive ceramic scaffolds have been proved to contribute to enhancing
osteoinduction and osseointegration. However, the poor mechanical property limits the …

Three-dimensional (3D) printing technology is a promising method for bone tissue
engineering applications. For enhanced bone regeneration, it is important to have printable …

Currently, clinically available orthopedic implants are extremely biocompatible but they lack
specific biological characteristics that allow for further interaction with surrounding tissues …

The present study provides a solvent-free processing method for establishing the ideal
porous 3-dimension (3D) scaffold filled with different ratios of calcium silicate-based (CS) …

Bone tissue engineering is a promising solution for advanced bone defect reconstruction
after severe trauma. In bone tissue engineering, scaffolds in three-dimensional (3D) …

3D Printed biodegradable polymeric scaffolds are critical to repair a bone defect, which can
provide the individual porous and network microenvironments for cell attachment and bone …

Calcium silicate (CS) is a suitable substrate for bone tissue engineering because it can
provide bioactive ions like Si 4+ and Ca 2+ to promote bone regeneration. However, the …

Critical sized craniofacial defects are among the most challenging bone defects to repair,
due to the anatomical complexity and aesthetic importance. In this study, a polylactic …

Synthetic biomaterials combined with cells and osteogenic factors represent a promising
approach for the treatment of a number of orthopedic diseases, such as bone trauma and …