Polyamines are essential for the proliferation, differentiation, and development of
eukaryotes. They include spermine, spermidine, and the diamine precursor putrescine, and …

The polyamines spermidine and spermine and their diamine precursor putrescine are
naturally occurring, polycationic alkylamines that are essential for eukaryotic cell growth …

The chemically simple, biologically complex eukaryotic polyamines, spermidine and
spermine, are positively charged alkylamines involved in many crucial cellular processes …

Polyamines are small organic cations that are essential for normal cell growth and
development in eukaryotes. Under normal physiological conditions, intracellular polyamine …

Polyamines are ubiquitous positively charged amines found in all organisms. These
molecules play a crucial role in many biological functions including cell growth, gene …

The amino-acid-derived polyamines have long been associated with cell growth and cancer,
and specific oncogenes and tumour-suppressor genes regulate polyamine metabolism …

Polyamines, including spermine, spermidine, and the precursor diamine, putrescine, are
naturally occurring polycationic alkylamines that are required for eukaryotic cell growth …

Polyamines are essential for the growth and proliferation of mammalian cells and are
intimately involved in biological mechanisms such as DNA replication, RNA transcription …

Advances in our understanding of the metabolism and molecular functions of polyamines
and their alterations in cancer have led to resurgence in the interest of targeting polyamine …

Polyamines are aliphatic cations with multiple functions and are essential for life. Cellular
polyamine levels are regulated by multiple pathways such as synthesis from amino acid …