A well plate-based GelMA photo-crosslinking system with tunable hydrogel mechanical properties to regulate the PTH-mediated osteogenic fate
K Paek, S Woo, SJ Song, MK Kim, K Yi, S Chung… - …, 2024 - iopscience.iop.org
Versatile and efficient regulation of the mechanical properties of the extracellular matrix is
crucial not only for understanding the dynamic changes in biological systems, but also for …
crucial not only for understanding the dynamic changes in biological systems, but also for …
Tuning Physical Properties of GelMA Hydrogels through Microarchitecture for Engineering Osteoid Tissue
E Walejewska, FPW Melchels, A Paradiso… - …, 2023 - ACS Publications
Gelatin methacryloyl (GelMA) hydrogels have gained significant attention due to their
biocompatibility and tunable properties. Here, a new approach to engineer GelMA-based …
biocompatibility and tunable properties. Here, a new approach to engineer GelMA-based …
Integrating Mechanics and Bioactivity: A Detailed Assessment of Elasticity and Viscoelasticity at Different Scales in 2D Biofunctionalized PEGDA Hydrogels for …
C López-Serrano, Y Côté-Paradis… - … Applied Materials & …, 2024 - ACS Publications
Methods for promoting and controlling the differentiation of human mesenchymal stem cells
(hMSCs) in vitro before in vivo transplantation are crucial for the advancement of tissue …
(hMSCs) in vitro before in vivo transplantation are crucial for the advancement of tissue …
Photoresponsive hydrogels with photoswitchable mechanical properties allow time-resolved analysis of cellular responses to matrix stiffening
As cell function and phenotype can be directed by the mechanical characteristics of the
surrounding matrix, hydrogels have become important platforms for cell culture systems, with …
surrounding matrix, hydrogels have become important platforms for cell culture systems, with …
Regulation of stem cell fate in a three‐dimensional micropatterned dual‐crosslinked hydrogel system
Micropatterning technology is a powerful tool for controlling the cellular microenvironment
and investigating the effects of physical parameters on cell behaviors, such as migration …
and investigating the effects of physical parameters on cell behaviors, such as migration …
Dynamic stiffening hydrogel with instructive stiffening timing modulates stem cell fate in vitro and enhances bone remodeling in vivo
X Li, S Liu, S Han, Q Sun, J Yang… - Advanced …, 2023 - Wiley Online Library
Biomechanical stimuli derived from the extracellular matrix (ECM) extremely tune stem cell
fate through 3D and spatiotemporal changes in vivo. The matrix stiffness is a crucial factor …
fate through 3D and spatiotemporal changes in vivo. The matrix stiffness is a crucial factor …
Biofabrication of cell-laden gelatin methacryloyl hydrogels with incorporation of silanized hydroxyapatite by visible light projection
Gelatin methacryloyl (GelMA) hydrogel is a photopolymerizable biomaterial widely used for
three-dimensional (3D) cell culture due to its high biocompatibility. However, the drawback …
three-dimensional (3D) cell culture due to its high biocompatibility. However, the drawback …
Photo-driven dynamic hydrogel modulates bone marrow mesenchymal stem cells behavior for enhanced cartilage regeneration
Regenerating damaged cartilage remains a challenge due to limited cell availability and
inefficient chondrogenic differentiation. Here, we present a photo-driven dynamic hydrogel …
inefficient chondrogenic differentiation. Here, we present a photo-driven dynamic hydrogel …
Soft hydrogels for balancing cell proliferation and differentiation
Hydrogels have been widely explored for the delivery of cells in a variety of regenerative
medicine applications due to their ability to mimic both the biochemical and physical cues of …
medicine applications due to their ability to mimic both the biochemical and physical cues of …
Photo-crosslinkable, bone marrow-derived mesenchymal stem cells-encapsulating hydrogel based on collagen for osteogenic differentiation
T Zhang, H Chen, Y Zhang, Y Zan, T Ni, M Liu… - Colloids and Surfaces B …, 2019 - Elsevier
Many patients suffer from bone injury and self-regeneration is not effective. Developing new
strategies for effective bone injury repair is highly desired. Herein, collagen, an important …
strategies for effective bone injury repair is highly desired. Herein, collagen, an important …