Metabolic Regulations of Smilax china L. against β-Amyloid Toxicity in Caenorhabditis elegans

L Yan, Y Deng, Y Du, X Fang, X Fang, Q Zhang - Metabolites, 2024 - mdpi.com
Smilax china L.(Chinaroot) is a natural herb that has multiple uses, such as being used to
make tea and food. Both its roots and leaves have different uses due to their unique …

Ligusticum chuanxiong Hort as a medicinal and edible plant foods: Antioxidant, anti-aging and neuroprotective properties in Caenorhabditis elegans

Y Qin, F Chen, Z Tang, H Ren, Q Wang… - Frontiers in …, 2022 - frontiersin.org
Ligusticum chuanxiong Hort.(CX) is a medicinal and edible plant including a variety of active
substances, which may be an available resource for the treatment of related diseases. To …

[HTML][HTML] Antioxidant and Neuroprotective Effects of Seed Oils from Trichosanthes kirilowii and T. laceribractea in Caenorhabditis elegans: A Comparative Analysis …

W Wang, S Li, Y Zhu, X Cui, Z Sheng, H Wang… - Antioxidants, 2024 - mdpi.com
Excess reactive oxygen species (ROS) can accelerate amyloid β (Aβ) aggregation and tau
protein hyperphosphorylation in neuron cells, which further leads to neurodegenerative …

Neuroprotective Effects of Extracts from Tiger Milk Mushroom Lignosus rhinocerus Against Glutamate-Induced Toxicity in HT22 Hippocampal Neuronal Cells and …

P Kittimongkolsuk, N Pattarachotanant… - Biology, 2021 - mdpi.com
Simple Summary Neurodegenerative diseases are recognized as one of the major public
health issues in aging populations worldwide. High reactive oxygen species (ROS) cause …

Aquilaria crassna Leaf Extract Ameliorates Glucose-Induced Neurotoxicity In Vitro and Improves Lifespan in Caenorhabditis elegans

N Pattarachotanant, N Sornkaew, W Warayanon… - Nutrients, 2022 - mdpi.com
Hyperglycemia is one of the important causes of neurodegenerative disorders and aging.
Aquilaria crassna Pierre ex Lec (AC) has been widely used to relieve various health …

Exploring the therapeutic potential of Nelumbo nucifera leaf extract against amyloid-beta-induced toxicity in the Caenorhabditis elegans model of Alzheimer's …

YP Wen, HJ Fu, Q Chen, C Lan, DL Qin… - Frontiers in …, 2024 - frontiersin.org
Introduction: Alzheimer's disease (AD) represents a critical global health challenge with
limited therapeutic options, prompting the exploration of alternative strategies. A key …

Polygonum multiflorum Thunb extract extended the lifespan and healthspan of Caenorhabditis elegans via DAF-16/SIR-2.1/SKN-1

ML Sun, XY Chen, JJ Cao, XH Cui, HB Wang - Food & Function, 2021 - pubs.rsc.org
Polygonum multiflorum Thunb (PMT), as a traditional Chinese herbal medicine, has been
widely used in the prevention and treatment of aging-related diseases, including Alzheimer's …

Folium Hibisci Mutabilis extract, a potent autophagy enhancer, exhibits neuroprotective properties in multiple models of neurodegenerative diseases

CL He, Y Tang, X Chen, T Long, YN He, J Wei, JM Wu… - Phytomedicine, 2023 - Elsevier
Background Protein aggregates are considered key pathological features in
neurodegenerative diseases (NDs). The induction of autophagy can effectively promote the …

An extract of Rosaceae, Solanaceae and Zingiberaceae increases health span and mobility in Caenorhabditis elegans

S Hughes, N Kolsters, D van de Klashorst, E Kreuter… - BMC nutrition, 2022 - Springer
Abstract Background Members of the Rosaceae, Solanaceae and Zingiberaceae families
which include fruits such as cherries, tomatoes and ginger are known to have health …

Oolonghomobisflavans from Camellia sinensis increase Caenorhabditis elegans lifespan and healthspan

C Duangjan, SP Curran - Geroscience, 2022 - Springer
Tea polyphenols are widely considered as excellent antioxidant agents which can contribute
to human health and longevity. However, the identification of the active biomolecules in …