Timeline of FDA-approved targeted therapy for cholangiocarcinoma

SM Cho, A Esmail, A Raza, S Dacha, M Abdelrahim - Cancers, 2022 - mdpi.com
Simple Summary Cholangiocarcinoma constitutes around 3% of gastrointestinal cancers,
and mortality from this cancer has been rising in the recent decades. Many cases of …

Novel targeted treatment options for advanced cholangiocarcinoma

A Mahipal, A Kommalapati, SH Tella… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Surgical resection remains the mainstay of potentially curative treatment in the
early stages of cholangiocarcinoma, whereas for the advanced stage, systemic …

Targeted therapies in advanced cholangiocarcinoma

MH Storandt, PC Kurniali, A Mahipal, Z Jin - Life, 2023 - mdpi.com
Primary tumor resection and liver transplantation are the only curative treatment options for
the management of cholangiocarcinoma (CCA). However, for patients with advanced or …

Targeted therapies in cholangiocarcinoma: emerging evidence from clinical trials

MM Simile, P Bagella, G Vidili, A Spanu, R Manetti… - Medicina, 2019 - mdpi.com
Cholangiocarcinoma (CCA) is a highly-aggressive malignancy arising from the biliary tree,
characterized by a steady increase in incidence globally and a high mortality rate. Most …

Co-clinical trials: an innovative drug development platform for cholangiocarcinoma

B Balasubramanian, S Venkatraman, KZ Myint… - Pharmaceuticals, 2021 - mdpi.com
Cholangiocarcinoma (CCA), a group of malignancies that originate from the biliary tract, is
associated with a high mortality rate and a concerning increase in worldwide incidence. In …

[HTML][HTML] Updates in cholangiocarcinoma

K O'Hagan - Journal of the Advanced Practitioner in Oncology, 2022 - ncbi.nlm.nih.gov
Cholangiocarcinoma is a spectrum of invasive adenocarcinomas that arise in the
intrahepatic, perihilar, or distal biliary tree, and is classified by location. During JADPRO Live …

Advances in targeted therapy of cholangiocarcinoma

Y Li, J Yu, Y Zhang, C Peng, Y Song, S Liu - Annals of Medicine, 2024 - Taylor & Francis
Cholangiocarcinoma (CCA) is a malignant tumor originating in the bile duct and its
branching epithelium. Due to its high heterogeneity, there are no specific clinical indications …

Updates in the use of targeted therapies for the treatment of cholangiocarcinoma

E Lodl, B Ramnaraign, I Sahin… - Journal of Oncology …, 2023 - journals.sagepub.com
Objective Many patients with cholangiocarcinoma (CCA) are not surgical candidates, and
the survival benefit of chemotherapy is less than 12 months. Several mutations and …

Cholangiocarcinoma: investigations into pathway-targeted therapies

I Ntanasis-Stathopoulos, DI Tsilimigras… - Expert Review of …, 2020 - Taylor & Francis
Introduction Cholangiocarcinoma is a malignant disease of the biliary tract and accounts for
3% of all gastrointestinal tumors. Surgical intervention is currently the only potentially …

Emerging Therapies in Management of Cholangiocarcinoma

J Speckart, V Rasmusen, Z Talib, DA GnanaDev… - Cancers, 2024 - mdpi.com
Simple Summary This paper delves into the latest developments in the emerging therapies
for cholangiocarcinoma, with a focus on precision medicine, immunotherapy, and targeted …