[HTML][HTML] Demystifying solid targets: Simple and rapid distribution-scale production of [68Ga] GaCl3 and [68Ga] Ga-PSMA-11
J Svedjehed, M Pärnaste, K Gagnon - Nuclear Medicine and Biology, 2022 - Elsevier
Background As the demand for 68 Ga continues to grow, there is increasing interest in
single-to-multi-Curie production quantities of both [68 Ga] GaCl 3 and tracers such as [68 …
single-to-multi-Curie production quantities of both [68 Ga] GaCl 3 and tracers such as [68 …
Cyclotron-based production of 68Ga, [68Ga]GaCl3, and [68Ga]Ga-PSMA-11 from a liquid target
ME Rodnick, C Sollert, D Stark, M Clark… - EJNMMI …, 2020 - Springer
Purpose To optimize the direct production of 68 Ga on a cyclotron, via the 68 Zn (p, n) 68 Ga
reaction using a liquid cyclotron target. We Investigated the yield of cyclotron-produced 68 …
reaction using a liquid cyclotron target. We Investigated the yield of cyclotron-produced 68 …
Multi-curie production of gallium-68 on a biomedical cyclotron and automated radiolabelling of PSMA-11 and DOTATATE
H Thisgaard, J Kumlin, N Langkjær, J Chua… - EJNMMI radiopharmacy …, 2021 - Springer
Background With increasing clinical demand for gallium-68, commercial germanium-
68/gallium-68 ([68 Ge] Ge/[68 Ga] Ga) generators are incapable of supplying sufficient …
68/gallium-68 ([68 Ge] Ge/[68 Ga] Ga) generators are incapable of supplying sufficient …
Otto: a 4.04 GBq (109 mCi) 68Ge/68Ga generator, first of its kind - extended quality control and performance evaluation in the clinical production of [68Ga]Ga …
NN Waterhouse, A Amor-Coarasa… - EJNMMI …, 2020 - Springer
Background Here we report on the comprehensive quality control of a 4.04 GBq (109 mCi)
generator supplied by itG (Munich, Germany), and used for routine production of [68 Ga] Ga …
generator supplied by itG (Munich, Germany), and used for routine production of [68 Ga] Ga …
High-Yielding Radiosynthesis of [68Ga]Ga-PSMA-11 Using a Low-Cost Microfluidic Device
X Zhang, F Liu, AC Payne, ML Nickels… - Molecular Imaging and …, 2020 - Springer
Purpose Current PET radiotracer production models result in facility and operational costs
that scale prohibitively with the number of tracers synthesized, particularly those made as a …
that scale prohibitively with the number of tracers synthesized, particularly those made as a …
Improved purification of cyclotron [68Ga] GaCl3 for the production of 68Ga radiopharmaceuticals
Abstract Introduction Increased demand for NetSpot and Illuccix as requirement to receive
the respective Lutathera and Pluvicto radiotherapies, and monitor subsequent response to …
the respective Lutathera and Pluvicto radiotherapies, and monitor subsequent response to …
Optimization of the radiosynthesis of [68Ga] Ga-PSMA-11 using a Trasis MiniAiO synthesizer: do we need to heat and purify?
J Reverchon, F Khayi, M Roger… - Nuclear medicine …, 2020 - journals.lww.com
Methods: The radiosynthesis of [68 Ga] Ga PSMA-11 was performed using a Trasis MiniAio
synthesizer and a 68 Ge/68 Ga GalliaPharm generator supplied by Eckert & Ziegler, Berlin …
synthesizer and a 68 Ge/68 Ga GalliaPharm generator supplied by Eckert & Ziegler, Berlin …
Synthesis of [68 Ga] Ga-PSMA-11 using the iMiDEV™ microfluidic platform
O Ovdiichuk, Q Béen, L Tanguy, C Collet - Reaction Chemistry & …, 2023 - pubs.rsc.org
We report herein the first production of [68Ga] Ga-PSMA-11 based on a microfluidic
disposable cassette using the iMiDEV™ synthesizer. The main steps of synthesis, 68Ga …
disposable cassette using the iMiDEV™ synthesizer. The main steps of synthesis, 68Ga …
Continuation of comprehensive quality control of the itG 68Ge/68Ga generator and production of 68Ga-DOTATOC and 68Ga-PSMA-HBED-CC for clinical research …
A Amor-Coarasa, JM Kelly, M Gruca… - Nuclear Medicine and …, 2017 - Elsevier
Performance of a second itG 68 Ge/68 Ga generator system and production of 68 Ga-
DOTATOC and 68 Ga-PSMA-HBED-CC were tested over one year as an accompaniment to …
DOTATOC and 68 Ga-PSMA-HBED-CC were tested over one year as an accompaniment to …
Production of [68Ga]Ga‐PSMA: Comparing a manual kit‐based method with a module‐based automated synthesis approach
J Kleynhans, S Rubow, J le Roux… - Journal of Labelled …, 2020 - Wiley Online Library
The labeling of peptides with gallium‐68 is often initially performed by manual labeling, but
with high clinical demand, other alternatives are needed. Cold‐kits or automated synthesis …
with high clinical demand, other alternatives are needed. Cold‐kits or automated synthesis …
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