Increasing recognition of an association between obesity and many cancer types exists, but
how the myriad of local and systemic effects of obesity affect key cellular and non-cellular …

Obesity is a leading modifiable risk factor for the development of several epithelial
malignancies. In addition to increasing risk, obesity also confers worse prognosis for many …

There is compelling epidemiological evidence linking obesity to many tumours; however, the
molecular mechanisms fuelling this association are not clearly understood. Emerging …

Purpose There is growing evidence that inflammation is a central and reversible mechanism
through which obesity promotes cancer risk and progression. Methods We review recent …

Obesity and obesity-related disorders such as non-alcoholic fatty liver disease (NAFLD),
metabolic syndrome and type 2 diabetes exhibit an increased risk of developing various …

Excess adiposity is a risk factor for several cancers of the gastrointestinal system, specifically
oesophageal adenocarcinoma and colorectal, small intestine, pancreatic, liver, gallbladder …

Obesity is associated with increased risk and poor prognosis of many types of cancers.
Several obesity-related host factors involved in systemic metabolism can influence tumor …

The incidence of obesity in the Western world has increased dramatically during the recent
decades. Epidemiological data suggest that obesity is associated with an increased risk of …

Obesity is a risk factor for all major gastrointestinal cancers. With the rapid increase in the
prevalence of obesity worldwide, this link could lead to an elevated burden of cancers of the …

Historically, cancer research has focused on identifying mutations or amplification of genes
within the tumor, which informed the development of targeted therapies against affected …