Glycosyltransferase-catalyzed synthesis of bioactive oligosaccharides

CAGM Weijers, MCR Franssen, GM Visser - Biotechnology advances, 2008 - Elsevier
Mammalian cell surfaces are all covered with bioactive oligosaccharides which play an
important role in molecular recognition events such as immune recognition, cell–cell …

Enzyme-catalyzed oligosaccharide synthesis

Y Ichikawa, GC Look, CH Wong - Analytical biochemistry, 1992 - Elsevier
Cell-surface carbohydrates and their conjugates are involved in many types of molecular
recognition. This review describes recent developments in enzyme-catalyzed …

Oligosaccharide synthesis by glycosynthases

G Perugino, A Trincone, M Rossi, M Moracci - TRENDS in Biotechnology, 2004 - cell.com
Oligosaccharide synthesis is becoming increasingly important to the pharmaceutical
industry because these biomolecules have potential application as therapeutics. Enzymatic …

Glycosyl hydrolases and glycosyltransferases in the synthesis of oligosaccharides

A Trincone, A Giordano - Current Organic Chemistry, 2006 - ingentaconnect.com
Glycobiology and related disciplines have received an enormous interest in recent years as
they shed new light on the functional roles of carbohydrates in biological events leading to …

Biocatalytic synthesis of oligosaccharides

MM Palcic - Current opinion in biotechnology, 1999 - Elsevier
Tremendous advances in biocatalytic approaches to oligosaccharide synthesis have taken
place in the past two years. The use of isolated enzymes, both glycosyltransferases and …

Glycosyltransferase-catalyzed synthesis of non-natural oligosaccharides

R Öhrlein - Biocatalysis-From Discovery to Application, 1999 - Springer
Enzymes are indispensable tools in modern organic synthesis. Recent progress in cloning
techniques, microbiology and protein purification supply an ever growing number and …

Chemoenzymatic synthesis of oligosaccharides and glycoproteins

S Hanson, M Best, MC Bryan, CH Wong - Trends in biochemical sciences, 2004 - cell.com
Oligosaccharides are involved in a wide range of biological processes including, for
example, bacterial and viral infection, cancer metastasis, the blood-clotting cascade and …

Utilization of glycosyltransferases as a seamless tool for synthesis and modification of the oligosaccharides-A review

MY Ali, F Liaqat, MI Khazi, S Sethupathy… - International Journal of …, 2023 - Elsevier
Glycosyltransferases (GTs) catalyze the transfer of active monosaccharide donors to
carbohydrates to create a wide range of oligosaccharide structures. GTs display strong …

A new multi-enzyme system for a one-pot synthesis of sialyl oligosaccharides: Combined use of β-galactosidase and α (26)-sialyltransferase coupled with …

GF Herrmann, Y Ichikawa, C Wandrey, FCA Gaeta… - Tetrahedron letters, 1993 - Elsevier
A New Multi-Enzyme System for a One-Pot Synthesis of Sialyl Oligosaccharides: Combined
Use of p-Galactosidase and a(2,6)-Siaiylt Page 1 Tetrahedron Lctten.. Vol. 34, No. 19. pp …

Enzyme-catalyzed synthesis of oligosaccharides that contain functionalized sialic acids

MD Chappell, RL Halcomb - Journal of the American Chemical …, 1997 - ACS Publications
The explosion of discoveries during the past decade that many cellular processes are
mediated by cell-surface carbohydrates and glycoconjugates1 has renewed the interest of …