Tetracycline to prevent epidermal growth factor receptor inhibitor‐induced skin rashes: Results of a placebo‐controlled trial from the North Central Cancer Treatment …

A Jatoi, K Rowland, JA Sloan, HM Gross… - … Journal of the …, 2008 - Wiley Online Library
BACKGROUND. Epidermal growth factor receptor (EGFR) inhibitors are effective cancer
therapies, but they are reported to cause a rash in> 50% of patients. In the current study, the …

Prophylactic tetracycline does not diminish the severity of epidermal growth factor receptor (EGFR) inhibitor-induced rash: results from the North Central Cancer …

A Jatoi, SR Dakhil, JA Sloan, JW Kugler… - Supportive Care in …, 2011 - Springer
Purpose Previous studies suggest tetracycline and other antibiotics lessen the severity of
epidermal growth factor receptor (EGFR) inhibitor-induced rash. This study sought to confirm …

Does sunscreen prevent epidermal growth factor receptor (EGFR) inhibitor–induced rash? Results of a placebo-controlled trial from the North central cancer treatment …

A Jatoi, A Thrower, JA Sloan, PJ Flynn… - The …, 2010 - academic.oup.com
Abstract Purpose. Rash occurs in> 50% of patients prescribed epidermal growth factor
receptor (EGFR) inhibitors. This study was undertaken to determine whether sunscreen …

Antibiotic prophylaxis for skin toxicity induced by antiepidermal growth factor receptor agents: a systematic review and meta‐analysis

F Petrelli, K Borgonovo, M Cabiddu… - British Journal of …, 2016 - academic.oup.com
Topical and systemic prophylactic measures, which are administered before the
development of epidermal growth factor receptor (EGFR)‐related acneiform rash, are …

A review of the treatment options for skin rash induced by EGFR-targeted therapies: evidence from randomized clinical trials and a metaanalysis

J Ocvirk, S Heeger, P McCloud… - Radiology and oncology, 2013 - sciendo.com
Background. Agents targeting the epidermal growth factor receptor (EGFR) are amongst the
most extensively used of the targeted agents in the therapy of some of the most common …

Dermatologic infections in cancer patients treated with epidermal growth factor receptor inhibitor therapy

RE Eilers Jr, M Gandhi, JD Patel… - Journal of the …, 2010 - academic.oup.com
Background Patients treated with epidermal growth factor receptor inhibitors (EGFRIs)
frequently experience dermatologic toxic effects. Whereas the impact of these effects on …

Epidermal growth factor receptor inhibitors: a review of cutaneous adverse events and management

K Chanprapaph, V Vachiramon… - Dermatology …, 2014 - Wiley Online Library
Epidermal growth factor inhibitors (EGFRI), the first targeted cancer therapy, are currently an
essential treatment for many advance‐stage epithelial cancers. These agents have the …

Do patients die from rashes from epidermal growth factor receptor inhibitors? A systematic review to help counsel patients about holding therapy

A Jatoi, PL Nguyen - The Oncologist, 2008 - academic.oup.com
Rash from epidermal growth factor receptor inhibitors is common and negatively impacts the
quality of life of cancer patients. Published guidelines recommend holding cancer therapy if …

[HTML][HTML] Clinical signs, pathophysiology and management of skin toxicity during therapy with epidermal growth factor receptor inhibitors

S Segaert, E Van Cutsem - Annals of oncology, 2005 - Elsevier
The last few years, new therapies targeting the epidermal growth factor receptor (EGFR)
have shown their efficacy in the treatment of several types of cancer. Monoclonal antibodies …

Acneiform rash induced by EGFR inhibitors: review of the literature and new insights

G Fabbrocini, L Panariello, G Caro… - Skin appendage …, 2015 - karger.com
Acneiform rash is the most common side effect of epidermal growth factor receptor (EGFR)
inhibitors (EGFRis), and it occurs in 50-100% of patients. This condition can affect the quality …