A route for investigating psoriasis: from the perspective of the pathological mechanisms and therapeutic strategies of cancer

X Wu, Y Ma, L Wang, X Qin - International Journal of Molecular Sciences, 2023 - mdpi.com
Psoriasis is an incurable skin disease that develops in about two-thirds of patients before the
age of 40 and requires lifelong treatment; its pathological mechanisms have not been fully …

Cellular mechanisms of psoriasis pathogenesis: a systemic review

M Wu, C Dai, F Zeng - Clinical, cosmetic and investigational …, 2023 - Taylor & Francis
Psoriasis is a common inflammatory skin disease characterized by abnormal proliferation of
epidermal keratinocytes and massive infiltration of inflammatory cells. Many kinds of cells …

Challenges and future trends in the treatment of psoriasis

HJ Lee, M Kim - International Journal of Molecular Sciences, 2023 - mdpi.com
Psoriasis is a chronic inflammatory skin disorder, and current treatments include topical
therapies, phototherapy, systemic immune modulators, and biologics, aiming to alleviate …

A multidisciplinary approach to patients with psoriasis and a history of malignancies or on-treatment for solid tumors: A narrative literature review

N Denaro, G Nazzaro, G Murgia, F Scarfì… - International Journal of …, 2023 - mdpi.com
Psoriasis is a chronic immune-mediated disease that is linked to an increased risk of cancer.
Although numerous studies have explored whether neoplasms are concurrent conditions or …

Signaling pathways and targeted therapies for psoriasis

J Guo, H Zhang, W Lin, L Lu, J Su… - Signal Transduction and …, 2023 - nature.com
Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Psoriasis: pathogenesis, comorbidities, and therapy updated

N Kanda - International journal of molecular sciences, 2021 - mdpi.com
Psoriasis is a chronic inflammatory skin disease characterized by IL-17-dominant abnormal
innate and acquired immunity, and the hyperproliferation and aberrant differentiation of …

Recent advances in psoriasis therapy: Trends and future prospects

A Singh, TS Easwari - Current Drug Targets, 2021 - ingentaconnect.com
Background: Psoriasis is a challenging skin disorder due to its chronicity, high rate of
prevalence, disability, comorbidity and disfiguration. It is a multi-system disorder that …

Pathogenesis, multi-omics research, and clinical treatment of psoriasis

J Yu, Q Zhao, X Wang, H Zhou, J Hu, L Gu, Y Hu… - Journal of …, 2022 - Elsevier
Psoriasis is a common inflammatory skin disease involving interactions between
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …

Advances in the pathogenesis of psoriasis: from keratinocyte perspective

X Zhou, Y Chen, L Cui, Y Shi, C Guo - Cell death & disease, 2022 - nature.com
Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …

Molecular pathophysiology of psoriasis and molecular targets of antipsoriatic therapy

E Rácz, EP Prens - Expert reviews in molecular medicine, 2009 - cambridge.org
Psoriasis is a chronic inflammatory skin disease characterised by elevated red scaly
plaques on specific body sites. Histologically, the plaques are defined by epidermal …