The gut metagenomics and metabolomics signature in patients with inflammatory bowel disease

X Xu, DKW Ocansey, S Hang, B Wang, S Amoah, C Yi… - Gut Pathogens, 2022 - Springer
Inflammatory bowel disease (IBD), a chronic gut immune dysregulation and dysbiosis
condition is rapidly increasing in global incidence. Regardless, there is a lack of ideal …

Microbiome and metabolome in inflammatory bowel disease

KG Upadhyay, DC Desai, TF Ashavaid… - Journal of …, 2023 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic gastrointestinal disease of unknown etiology,
involving complex interactions between the gut microbiome and host immune response. The …

Metabolomics as a promising resource identifying potential biomarkers for inflammatory bowel disease

C Bauset, L Gisbert-Ferrándiz… - Journal of Clinical …, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a relapsing chronic disorder of the gastrointestinal tract
characterized by disruption of epithelial barrier function and excessive immune response to …

Microbiome, metabolome and inflammatory bowel disease

I Ahmed, BC Roy, SA Khan, S Septer, S Umar - Microorganisms, 2016 - mdpi.com
Inflammatory Bowel Disease (IBD) is a multifactorial disorder that conceptually occurs as a
result of altered immune responses to commensal and/or pathogenic gut microbes in …

[HTML][HTML] Gut microbial metabolome in inflammatory bowel disease: From association to therapeutic perspectives

M Li, L Yang, C Mu, Y Sun, Y Gu, D Chen, T Liu… - Computational and …, 2022 - Elsevier
Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis
(UC), is a set of clinically chronic, relapsing gastrointestinal inflammatory disease and lacks …

Using metabolomic analysis to understand inflammatory bowel diseases

HM Lin, NA Helsby, DD Rowan… - Inflammatory bowel …, 2011 - academic.oup.com
Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBD)
attributed to a dysregulated immune response towards intestinal microbiota. Although …

Microbiome and metabolome features in inflammatory bowel disease via multi-omics integration analyses across cohorts

L Ning, YL Zhou, H Sun, Y Zhang, C Shen… - Nature …, 2023 - nature.com
The perturbations of the gut microbiota and metabolites are closely associated with the
progression of inflammatory bowel disease (IBD). However, inconsistent findings across …

Alterations in lipid, amino acid, and energy metabolism distinguish Crohn's disease from ulcerative colitis and control subjects by serum metabolomic profiling

EA Scoville, MM Allaman, CT Brown, AK Motley… - Metabolomics, 2018 - Springer
Introduction Biomarkers are needed in inflammatory bowel disease (IBD) to help define
disease activity and identify underlying pathogenic mechanisms. We hypothesized that …

Metabolomics insights into inflammatory bowel disease: a comprehensive review

L Aldars-Garcia, JP Gisbert, M Chaparro - Pharmaceuticals, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic, complex relapsing disorder characterised by
immune dysregulation, gut microbiota alteration, and disturbed intestinal permeability. The …

Gut microbial metabolite-mediated regulation of the intestinal barrier in the pathogenesis of inflammatory bowel disease

N Iyer, SC Corr - Nutrients, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic inflammatory disease. The disease has a
multifactorial aetiology, involving genetic, microbial as well as environmental factors. The …