Objectives Cancer is one of the leading causes of death throughout the world. Current
therapy options suffer from the major limitations of side effects and drug resistance. Thus …

In order to take the advantages of the anticancer properties of benzimidazoles and
hydrazones, we synthesized new 4‐(5‐chloro‐1 H‐benzimidazol‐2‐yl)‐benzoic acid …

Background: In recent years, thiazole derivatives incorporated with hydrazone moiety have
attracted a great deal of interest due to their pivotal role in the field of current cancer …

Based on the biologically active heterocycle compounds, a series of new benzimidazole-
hydrazone derivatives (3a-3j) were synthesized, starting from 4-(6-chloro-1H-benzimidazol …

Background A series of benzimidazole derivatives was developed and its chemical scaffolds
were authenticated by NMR, IR, elemental analyses and physicochemical properties. The …

In the present study, a novel series of 2-(2-(3-aryl-5-substituted-1, 3, 4-thiadiazol-2 (3H)-
ylidene) hydrazinyl)-4, 4-diphenyl-1H-imidazol-5 (4H)-one derivatives were designed and …

Based on the biologically active heterocycle compounds, a series of new benzimidazole-
hydrazone derivatives (3a-3j) were synthesized, starting from 4-(6-chloro-1H-benzimidazol …

In the present study o-phenylenediamine and naphtene-1-acetic acid/2-naphthoxyacetic
acid were used as a starting material through a series of steps and 2-(naphthalen-1 …

In order to explore and develop new anticancer agents, three series of 2-
phenylbenzimidazoles, 15–46, were condensed under simple and mild conditions using …

A novel class of acetylhydrazone derivatives (5a–x) containing 2-(phenylthiomethyl)-1H-
benzo-[d]-imidazole moieties are synthesizer, and their antitumor activities against A549 …