Background Among women with breast cancer who undergo breast-conserving surgery
(BCS), 20-25% require further surgery due to close or involved margins. Improved …

Background: In all, 70% of women with breast cancer who require surgical intervention
undergo breast-conserving surgery (BCS). Of these 20–25% of patients will require a further …

In early-stage breast cancer, the primary treatment option for most women is breast-
conserving surgery (BCS). There is a clear need for more accurate techniques to assess …

Background: CLI combines optical and molecular imaging properties by detecting visible
light emitted by 18 F-FDG accumulating in cancer cells. Its high-resolution and portable …

Methods: To date 8 of 30 patients have been recruited (REC reference 14/WM/0050).
Patients received 5 MBq/kg 18 F-FDG 1–2 hours prior to surgery. 99m Tc dose was …

13 Objectives A first-in-woman clinical trial in breast-conserving surgery is currently being
conducted to evaluate intraoperative 18 F-FDG Cerenkov Luminescence Imaging (CLI) of …

Introduction In women undergoing breast-conserving surgery (BCS), 20–25% require a re-
operation as a result of incomplete tumour resection. An intra-operative technique to assess …

Background and Objectives Current methods of intraoperative breast cancer margin
assessment are labor intensive, not fully reliable, and time consuming; therefore novel …

DISCUSSION Recent advances in nuclear imaging have enabled the development of
relatively cost-effective and portable devices to provide intraoperative guidance regarding …

Objective To evaluate the feasibility and accuracy of near-infrared fluorescence imaging
technology for assessing margins during breast-conserving surgery for breast cancer …