Homology modelling of the human adenosine A 2B receptor based on X-ray structures of bovine rhodopsin, the β 2-adrenergic receptor and the human adenosine A …
FF Sherbiny, AC Schiedel, A Maaß… - Journal of computer-aided …, 2009 - Springer
A three-dimensional model of the human adenosine A 2B receptor was generated by means
of homology modelling, using the crystal structures of bovine rhodopsin, the β 2-adrenergic …
of homology modelling, using the crystal structures of bovine rhodopsin, the β 2-adrenergic …
Molecular modeling of A1 and A2A adenosine receptors: Comparison of rhodopsin‐ and β2‐adrenergic‐based homology models through the docking studies
O Yuzlenko, K Kieć‐Kononowicz - Journal of computational …, 2009 - Wiley Online Library
Adenosine receptors (ARs) are members of the superfamily of G protein‐coupled receptors.
The homology models of adenosine A1 and A2A receptors were constructed. The high …
The homology models of adenosine A1 and A2A receptors were constructed. The high …
Evaluation of Homology Modeling of G-Protein-Coupled Receptors in Light of the A2A Adenosine Receptor Crystallographic Structure
AA Ivanov, D Barak, KA Jacobson - Journal of medicinal chemistry, 2009 - ACS Publications
Homology modeling of the human A2A adenosine receptor (AR) based on bovine rhodopsin
predicted a protein structure that was very similar to the recently determined crystallographic …
predicted a protein structure that was very similar to the recently determined crystallographic …
Computer aided comparative analysis of the binding modes of the adenosine receptor agonists for all known subtypes of adenosine receptors
AA Ivanov, VA Palyulin, NS Zefirov - Journal of Molecular Graphics and …, 2007 - Elsevier
Molecular models of all known subtypes (A1, A2A, A2B, and A3) of the human adenosine
receptors were built in homology with bovine rhodopsin. These models include the …
receptors were built in homology with bovine rhodopsin. These models include the …
Novel approaches for modeling of the A1 adenosine receptor and its agonist binding site
H Gutiérrez‐de‐Terán, NB Centeno… - Proteins: Structure …, 2004 - Wiley Online Library
The present work describes the building of a human A1 adenosine receptor (hA1AR) model,
based on the X‐ray crystal structure of bovine rhodopsin, and its use as a basis for the …
based on the X‐ray crystal structure of bovine rhodopsin, and its use as a basis for the …
Adenosine receptor modeling: what does the A2A crystal structure tell us?
D Dal Ben, C Lambertucci, G Marucci… - Current Topics in …, 2010 - ingentaconnect.com
For a long time, there have been no experimentally determined structural data for any
adenosine receptor (AR) and the only approach available for making structure/function …
adenosine receptor (AR) and the only approach available for making structure/function …
Human A3 adenosine receptor as versatile G protein-coupled receptor example to validate the receptor homology modeling technology
E Morizzo, S Federico, G Spalluto… - Current pharmaceutical …, 2009 - ingentaconnect.com
The development of ligands for the A3 adenosine receptor (AR) has been directed mainly by
traditional medicinal chemistry, but the influence of structure-based approaches is …
traditional medicinal chemistry, but the influence of structure-based approaches is …
A 3D model of the human A1 adenosine receptor. An evaluation of the binding free-energy with ligands.
AM Bianucci, MU Bigi, G Biagi, I Giorgi… - Drug design and …, 1998 - europepmc.org
A model of A1 adenosine receptor was built on the basis of the prediction of transmembrane
helices made by PHDtopology and forcing the rough initial model over the scaffold of the …
helices made by PHDtopology and forcing the rough initial model over the scaffold of the …
Molecular Modeling Studies of Human A3 Adenosine Antagonists: Structural Homology and Receptor Docking
S Moro, AH Li, KA Jacobson - Journal of chemical information and …, 1998 - ACS Publications
Molecular modeling studies were conducted on various chemically diverse classes of
human A3 adenosine receptor antagonists (hA3ANTs), such as adenines, xanthines …
human A3 adenosine receptor antagonists (hA3ANTs), such as adenines, xanthines …
Binding site analysis of full-length α1a adrenergic receptor using homology modeling and molecular docking
A Pedretti, ME Silva, L Villa, G Vistoli - Biochemical and biophysical …, 2004 - Elsevier
The recent availability of crystal structure of bovine rhodopsin offers new opportunities in
order to approach the construction of G protein coupled receptors. This study focuses the …
order to approach the construction of G protein coupled receptors. This study focuses the …