Brain‐derived neurotrophic factor and the development of structural neuronal connectivity

S Cohen‐Cory, AH Kidane, NJ Shirkey… - Developmental …, 2010 - Wiley Online Library
During development, neural networks are established in a highly organized manner, which
persists throughout life. Neurotrophins play crucial roles in the developing nervous system …

BDNF: a key factor with multipotent impact on brain signaling and synaptic plasticity

P Kowiański, G Lietzau, E Czuba, M Waśkow… - Cellular and molecular …, 2018 - Springer
Brain-derived neurotrophic factor (BDNF) is one of the most widely distributed and
extensively studied neurotrophins in the mammalian brain. Among its prominent functions …

Neurotrophin regulation of neural circuit development and function

H Park, M Poo - Nature Reviews Neuroscience, 2013 - nature.com
Brain-derived neurotrophic factor (BDNF)—a member of a small family of secreted proteins
that includes nerve growth factor, neurotrophin 3 and neurotrophin 4—has emerged as a …

[HTML][HTML] A simple role for BDNF in learning and memory?

C Cunha, R Brambilla, KL Thomas - Frontiers in molecular …, 2010 - frontiersin.org
Since its discovery almost three decades ago, the secreted neurotrophin brain-derived
neurotrophic factor (BDNF) has been firmly implicated in the differentiation and survival of …

Form follows function: BDNF and its involvement in sculpting the function and structure of synapses

M Zagrebelsky, M Korte - Neuropharmacology, 2014 - Elsevier
Neurotrophins are essential for multiple aspects of neuronal development and function.
Especially BDNF (brain-derived-neurotrophic-factor) has been shown to play an important …

[HTML][HTML] Pleiotropic effects of BDNF on the cerebellum and hippocampus: Implications for neurodevelopmental disorders

S Camuso, P La Rosa, MT Fiorenza, S Canterini - Neurobiology of disease, 2022 - Elsevier
Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
mammalian brain, essential not only to the development of the central nervous system but …

Activity-dependent dendritic release of BDNF and biological consequences

N Kuczewski, C Porcher, V Lessmann, I Medina… - Molecular …, 2009 - Springer
Network construction and reorganization is modulated by the level and pattern of synaptic
activity generated in the nervous system. During the past decades, neurotrophins, and in …

BDNF and synaptic plasticity, cognitive function, and dysfunction

B Lu, G Nagappan, Y Lu - Neurotrophic factors, 2014 - Springer
Among all neurotrophins, brain-derived neurotrophic factor (BDNF) stands out for its high
level of expression in the brain and its potent effects on synapses. It is now widely accepted …

Brain-derived neurotrophic factor (BDNF): novel insights into regulation and genetic variation

M Notaras, M van den Buuse - The Neuroscientist, 2019 - journals.sagepub.com
Since its discovery, brain-derived neurotrophic factor (BDNF) has spawned a literature that
now spans 35 years of research. While all neurotrophins share considerable overlap in …

Brain-derived neurotrophic factor is required for the maintenance of cortical dendrites

JA Gorski, SR Zeiler, S Tamowski… - Journal of …, 2003 - Soc Neuroscience
Brain-derived neurotrophic factor (BDNF) is thought to be involved in neuronal survival,
migration, morphological and biochemical differentiation, and modulation of synaptic …