[HTML][HTML] A phase II dose evaluation pilot feasibility randomized controlled trial of cholecalciferol in critically ill children with vitamin D deficiency (VITdAL-PICU study)

K O'Hearn, K Menon, HA Weiler, K Amrein… - BMC pediatrics, 2023 - Springer
Abstract Background Vitamin D deficiency (VDD) is highly prevalent in the pediatric
intensive care unit (ICU) and associated with worse clinical course. Trials in adult ICU …

[HTML][HTML] Study protocol for a phase II dose evaluation randomized controlled trial of cholecalciferol in critically ill children with vitamin D deficiency (VITdAL-PICU study …

D McNally, K Amrein, K O'Hearn, D Fergusson… - Pilot and Feasibility …, 2017 - Springer
Background Clinical research has recently demonstrated that vitamin D deficiency (VDD) is
highly prevalent in the pediatric intensive care unit (PICU) and associated with worse clinical …

[HTML][HTML] Vitamin D deficiency in critically ill children: a systematic review and meta-analysis

JD McNally, N Nama, K O'Hearn, M Sampson… - Critical Care, 2017 - Springer
Abstract Background Vitamin D deficiency (VDD) has been hypothesized not only to be
common but also to represent a potentially modifiable risk factor for greater illness severity …

Prospective pilot study evaluating a vitamin D3 loading dose in critically ill children with vitamin D deficiency

EW Covington, SL Jasper‐Trotter… - Fundamental & …, 2024 - Wiley Online Library
Background Vitamin D deficiency is a common finding in critically ill children. However, the
optimal supplementation strategy in this patient population is unknown. The objective of this …

[HTML][HTML] Correction of vitamin D deficiency in critically ill patients-VITdAL@ ICU study protocol of a double-blind, placebo-controlled randomized clinical trial

K Amrein, C Schnedl, A Berghold, TR Pieber… - BMC endocrine …, 2012 - Springer
Background Vitamin D deficiency is associated with multiple adverse health outcomes
including increased morbidity and mortality in the general population and in critically ill …

[HTML][HTML] Vitamin D deficiency and length of pediatric intensive care unit stay: a prospective observational study

J Sankar, W Lotha, J Ismail, C Anubhuti… - Annals of intensive …, 2016 - Springer
Background Due to the limited data available in the pediatric population and lack of
interventional studies to show that administration of vitamin D indeed improves clinical …

Vitamin D deficiency in pediatric critical care

JD McNally, K Amrein - Journal of Pediatric Intensive Care, 2016 - thieme-connect.com
Vitamin D deficiency (VDD) is a well-established cause of pediatric bone and muscle
disease. In addition, a role has been recognized for vitamin D in the health and stress …

The association of vitamin D status with pediatric critical illness

JD McNally, K Menon, P Chakraborty, L Fisher… - …, 2012 - publications.aap.org
OBJECTIVES: Vitamin D is a pleiotropic hormone important for the proper functioning of
multiple organ systems. It has been hypothesized that vitamin D deficiency could contribute …

Rapid normalization of vitamin D levels: a meta-analysis

JD McNally, K Iliriani, S Pojsupap, M Sampson… - …, 2015 - publications.aap.org
BACKGROUND: Vitamin D deficiency may represent a modifiable risk factor to improve
outcome in severe illness. The efficacy of high-dose regimens in rapid normalization of …

[HTML][HTML] Vitamin D status at admission and its association with mortality in children admitted to the pediatric intensive care unit

S Das, N Biswal, N Parameswaran, N Nanda - Cureus, 2020 - ncbi.nlm.nih.gov
Materials and methods A prospective observational study was conducted among 522
children admitted to the Pediatric Intensive Care Unit in the Pediatrics Department of the …