Sex differences in circadian timing systems: implications for disease

M Bailey, R Silver - Frontiers in neuroendocrinology, 2014 - Elsevier
Virtually every eukaryotic cell has an endogenous circadian clock and a biological sex.
These cell-based clocks have been conceptualized as oscillators whose phase can be reset …

Sex differences in circadian endocrine rhythms: clinical implications

NC Nicolaides, GP Chrousos - European Journal of …, 2020 - Wiley Online Library
Organisms have developed a highly conserved and tightly regulated circadian system, to
adjust their daily activities to day/night cycles. This system consists of a central clock, which …

Minireview: The neuroendocrinology of the suprachiasmatic nucleus as a conductor of body time in mammals

IN Karatsoreos, R Silver - Endocrinology, 2007 - academic.oup.com
Circadian rhythms in physiology and behavior are regulated by a master clock resident in
the suprachiasmatic nucleus (SCN) of the hypothalamus, and dysfunctions in the circadian …

Clocks on top: the role of the circadian clock in the hypothalamic and pituitary regulation of endocrine physiology

KJ Tonsfeldt, PE Chappell - Molecular and cellular endocrinology, 2012 - Elsevier
Recent strides in circadian biology over the last several decades have allowed researchers
new insight into how molecular circadian clocks influence the broader physiology of …

Two decades of circadian time

MH Hastings, ES Maywood… - Journal of …, 2008 - Wiley Online Library
Circadian rhythms coordinate our physiology at a fundamental level. Over the last 20 years,
we have witnessed a paradigm shift in our perception of what the clocks driving such …

[HTML][HTML] Mechanisms of communication in the mammalian circadian timing system

M Astiz, I Heyde, H Oster - International journal of molecular sciences, 2019 - mdpi.com
24-h rhythms in physiology and behaviour are organized by a body-wide network of
endogenous circadian clocks. In mammals, a central pacemaker in the hypothalamic …

The circadian system: a regulatory feedback network of periphery and brain

FN Buijs, L León-Mercado, M Guzmán-Ruiz… - …, 2016 - journals.physiology.org
Circadian rhythms are generated by the autonomous circadian clock, the suprachiasmatic
nucleus (SCN), and clock genes that are present in all tissues. The SCN times these …

Adrenal clocks and the role of adrenal hormones in the regulation of circadian physiology

A Leliavski, R Dumbell, V Ott… - Journal of biological …, 2015 - journals.sagepub.com
The mammalian circadian timing system consists of a master pacemaker in the
suprachiasmatic nucleus (SCN) and subordinate clocks that disseminate time information to …

Neuroendocrine underpinnings of sex differences in circadian timing systems

L Yan, R Silver - The Journal of steroid biochemistry and molecular …, 2016 - Elsevier
There are compelling reasons to study the role of steroids and sex differences in the
circadian timing system. A solid history of research demonstrates the ubiquity of circadian …

Interaction of central and peripheral clocks in physiological regulation

JL Barclay, AH Tsang, H Oster - Progress in brain research, 2012 - Elsevier
In mammals, circadian rhythms of physiology and behavior are regulated by a complex
network of cellular molecular oscillators distributed throughout the brain and peripheral …