Abstract Purpose of Review Pathological roles of macrophage migration inhibitory factor
(MIF) have recently been demonstrated in spondyloarthritis (SpA) preclinical models …

Spondyloarthritis (SpA), a type 3 immunity-mediated inflammatory arthritis, is a systemic
rheumatic disease that primarily affects the joints, spine, gut, skin, and eyes. Macrophage …

Objective To investigate the role of macrophage migration inhibitory factor (MIF) in the
pathogenesis of ankylosing spondylitis (AS). Methods Patients who met the modified New …

Background Osteoarthritis (OA) is the most prevalent form of arthritis and the major cause of
disability and overall diminution of quality of life in the elderly population. Currently there is …

The role of cytokines in the pathogenesis of rheumatoid arthritis (RA) has been a fertile area
of research in the last two decades. The strongest supporting evidence for the importance of …

Herenius et al.[1] have revealed that anti-TNF therapy diminishes serum levels of chemokine
chemerin and thus inhibits the recruitment of MIF-producing cells (macrophages, dendritic …

Macrophage migration inhibitory factor (MIF) enhances activation of leukocytes, endothelial
cells and fibroblast-like synoviocytes (FLS), thereby contributing to the pathogenesis of …

Macrophage migration inhibitory factor (MIF) is a pleiotropic pro-inflammatory cytokine with
many cellular targets in rheumatoid arthritis (RA). MIF has been reported to activate cells via …

Objectives To investigate the associations of miR-451 and macrophage migration inhibitory
factor (MIF) with disease activity, radiographic progression, and cytokine levels of ankylosing …

Introduction. Macrophage migration inhibitory factor (MIF) is a pleiotropic inflammatory
cytokine with upstream regulatory roles in innate and adaptive immunity and is implicated in …