Regulation of macrophage development and function in peripheral tissues
Macrophages are immune cells of haematopoietic origin that provide crucial innate immune
defence and have tissue-specific functions in the regulation and maintenance of organ …
defence and have tissue-specific functions in the regulation and maintenance of organ …
Macrophages: development and tissue specialization
C Varol, A Mildner, S Jung - Annual review of immunology, 2015 - annualreviews.org
Macrophages are myeloid immune cells that are strategically positioned throughout the
body tissues, where they ingest and degrade dead cells, debris, and foreign material and …
body tissues, where they ingest and degrade dead cells, debris, and foreign material and …
[HTML][HTML] Tissue-specific macrophages: how they develop and choreograph tissue biology
Macrophages are innate immune cells that form a 3D network in all our tissues, where they
phagocytose dying cells and cell debris, immune complexes, bacteria and other waste …
phagocytose dying cells and cell debris, immune complexes, bacteria and other waste …
Origin, development, and homeostasis of tissue‐resident macrophages
M Haldar, KM Murphy - Immunological reviews, 2014 - Wiley Online Library
Macrophages are versatile cells of the hematopoietic system that display remarkable
functional diversity encompassing innate immune responses, tissue development, and …
functional diversity encompassing innate immune responses, tissue development, and …
Origins and diversity of macrophages in health and disease
Macrophages are the first immune cells in the developing embryo and have a central role in
organ development, homeostasis, immunity and repair. Over the last century, our …
organ development, homeostasis, immunity and repair. Over the last century, our …
Developmental control of macrophage function
J Bonnardel, M Guilliams - Current opinion in immunology, 2018 - Elsevier
Highlights•We review the potential impact of cellular origin on the function of
macrophages.•We discuss the recent evidence for macrophages plasticity.•We also highlight …
macrophages.•We discuss the recent evidence for macrophages plasticity.•We also highlight …
Delineating the origins, developmental programs and homeostatic functions of tissue-resident macrophages
E Mass - International Immunology, 2018 - academic.oup.com
A literature covering 150 years of research indicates that macrophages are a diverse family
of professional phagocytes that continuously explore their environment, recognize and …
of professional phagocytes that continuously explore their environment, recognize and …
Transcriptional control of monocyte and macrophage development
D Kurotaki, H Sasaki, T Tamura - International immunology, 2017 - academic.oup.com
Monocytes and macrophages play critical roles in immune responses, tissue homeostasis
and disease progression. There are a number of functionally and phenotypically distinct …
and disease progression. There are a number of functionally and phenotypically distinct …
Monocytes and macrophages: developmental pathways and tissue homeostasis
Monocytes and macrophages have crucial and distinct roles in tissue homeostasis and
immunity, but they also contribute to a broad spectrum of pathologies and are thus attractive …
immunity, but they also contribute to a broad spectrum of pathologies and are thus attractive …
Tissue biology perspective on macrophages
Y Okabe, R Medzhitov - Nature immunology, 2016 - nature.com
Macrophages are essential components of mammalian tissues. Although historically known
mainly for their function in host defense and the clearance of apoptotic cells, macrophages …
mainly for their function in host defense and the clearance of apoptotic cells, macrophages …