[HTML][HTML] Multi-omics approaches in cancer research with applications in tumor subtyping, prognosis, and diagnosis

O Menyhárt, B Győrffy - Computational and structural biotechnology journal, 2021 - Elsevier
While cost-effective high-throughput technologies provide an increasing amount of data, the
analyses of single layers of data seldom provide causal relations. Multi-omics data …

[HTML][HTML] Integrative multi-omics approaches in cancer research: from biological networks to clinical subtypes

YJ Heo, C Hwa, GH Lee, JM Park, JY An - Molecules and cells, 2021 - Elsevier
Multi-omics approaches are novel frameworks that integrate multiple omics datasets
generated from the same patients to better understand the molecular and clinical features of …

Multi-omics analysis: Paving the path toward achieving precision medicine in cancer treatment and immuno-oncology

V Raufaste-Cazavieille, R Santiago… - Frontiers in Molecular …, 2022 - frontiersin.org
The acceleration of large-scale sequencing and the progress in high-throughput
computational analyses, defined as omics, was a hallmark for the comprehension of the …

A comparative study of multi-omics integration tools for cancer driver gene identification and tumour subtyping

A Sathyanarayanan, R Gupta… - Briefings in …, 2020 - academic.oup.com
Oncogenesis and cancer can arise as a consequence of a wide range of genomic
aberrations including mutations, copy number alterations, expression changes and …

Artificial intelligence-based multi-omics analysis fuels cancer precision medicine

X He, X Liu, F Zuo, H Shi, J Jing - Seminars in Cancer Biology, 2023 - Elsevier
With biotechnological advancements, innovative omics technologies are constantly
emerging that have enabled researchers to access multi-layer information from the genome …

Artificial intelligence (AI)-based systems biology approaches in multi-omics data analysis of cancer

N Biswas, S Chakrabarti - Frontiers in oncology, 2020 - frontiersin.org
Cancer is the manifestation of abnormalities of different physiological processes involving
genes, DNAs, RNAs, proteins, and other biomolecules whose profiles are reflected in …

The need for multi-omics biomarker signatures in precision medicine

M Olivier, R Asmis, GA Hawkins, TD Howard… - International journal of …, 2019 - mdpi.com
Recent advances in omics technologies have led to unprecedented efforts characterizing
the molecular changes that underlie the development and progression of a wide array of …

Onco‐multi‐OMICS approach: a new frontier in cancer research

S Chakraborty, MI Hosen, M Ahmed… - BioMed research …, 2018 - Wiley Online Library
The acquisition of cancer hallmarks requires molecular alterations at multiple levels
including genome, epigenome, transcriptome, proteome, and metabolome. In the past …

Machine learning: a new prospect in multi-omics data analysis of cancer

B Arjmand, SK Hamidpour, A Tayanloo-Beik… - Frontiers in …, 2022 - frontiersin.org
Cancer is defined as a large group of diseases that is associated with abnormal cell growth,
uncontrollable cell division, and may tend to impinge on other tissues of the body by different …

The crucial role of multiomic approach in cancer research and clinically relevant outcomes

M Lu, X Zhan - EPMA Journal, 2018 - Springer
Cancer with heavily economic and social burden is the hot point in the field of medical
research. Some remarkable achievements have been made; however, the exact …