[HTML][HTML] FAP and FAPI-PET/CT in malignant and non-malignant diseases: a perfect symbiosis?

K Dendl, SA Koerber, C Kratochwil, J Cardinale… - Cancers, 2021 - mdpi.com
Simple Summary FAPI represents a novel class of radiotracers demonstrating promising
results in terms of a high uptake in concordance with low background noise in several …

[HTML][HTML] FAPI-PET/CT in cancer imaging: a potential novel molecule of the century

R Huang, Y Pu, S Huang, C Yang, F Yang, Y Pu… - Frontiers in …, 2022 - frontiersin.org
Fibroblast activation protein (FAP), a type II transmembrane serine protease, is highly
expressed in more than 90% of epithelial tumors and is closely associated with various …

Fibroblast activation protein inhibitor PET/CT: a promising molecular imaging tool

P Sharma, SS Singh, S Gayana - Clinical nuclear medicine, 2021 - journals.lww.com
Purpose Fibroblast activation protein (FAP) is a cell membrane–bound serine peptidase,
overexpressed in cancer-associated fibroblasts and activated fibroblasts at wound …

[HTML][HTML] FAPI PET/CT imaging—an updated review

KR Chandekar, A Prashanth, S Vinjamuri, R Kumar - Diagnostics, 2023 - mdpi.com
Despite revolutionizing the field of oncological imaging, Positron Emission Tomography
(PET) with [18F] Fluorodeoxyglucose (FDG) as its workhorse is limited by a lack of specificity …

The latest developments in imaging of fibroblast activation protein

A Altmann, U Haberkorn, J Siveke - Journal of Nuclear Medicine, 2021 - Soc Nuclear Med
Fibroblast activation protein (FAP), a membrane-anchored peptidase, is highly expressed in
cancer-associated fibroblasts in more than 90% of epithelial tumors and contributes to …

Non-oncologic incidental uptake on FAPI PET/CT imaging

M Hotta, AC Rieger, MG Jafarvand… - The British journal of …, 2023 - academic.oup.com
Fibroblast-activation protein (FAP) is a serine protease classified in the dipeptidyl peptidase
4 (DPP4) family. FAP is predominantly expressed in activated fibroblasts such as the cancer …

FAPI PET: fibroblast activation protein inhibitor use in oncologic and nononcologic disease

Y Mori, K Dendl, J Cardinale, C Kratochwil, FL Giesel… - Radiology, 2023 - pubs.rsna.org
Gallium 68 (68Ga)–labeled fibroblast activation protein (FAP) inhibitor (FAPI) PET is based
on the molecular targeting of the FAP, which is known to be highly expressed in the major …

[HTML][HTML] FAPI-avid nonmalignant PET/CT findings: an expedited systematic review

M Bentestuen, N Al-Obaydi, HD Zacho - Seminars in Nuclear Medicine, 2023 - Elsevier
Fibroblast activation protein inhibitor (FAPI) is a promising tracer in oncologic positron
emission tomography/computed tomography (PET/CT). Numerous studies have …

Clinical summary of fibroblast activation protein inhibitor-based radiopharmaceuticals: cancer and beyond

M Li, MH Younis, Y Zhang, W Cai, X Lan - European journal of nuclear …, 2022 - Springer
Fibroblast activation protein (FAP) is a type II membrane-bound glycoprotein which is
overexpressed in cancer-associated fibroblasts and activated fibroblasts at wound …

[HTML][HTML] Novel FAP ligands enable improved imaging contrast in sarcoma patients due to FAPI-PET/CT

SA Koerber, R Finck, K Dendl, M Uhl, T Lindner… - European Journal of …, 2021 - Springer
Purpose A high expression of fibroblast activation protein (FAP) was observed in multiple
sarcomas, indicating an enormous potential for PET/CT using 68 Ga-radiolabeled inhibitors …