Abstract Background Patients with Alzheimer's disease (AD) are often co-morbid with
unprovoked seizures, making clinical diagnosis and management difficult. Although it has …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a rapid
accumulation of amyloid β (Aβ) protein in the hippocampus, which impairs synaptic …

Alzheimer's disease (AD) is characterized by the classical hallmarks of Aβ-deposition and
tau-pathology that are thought to ultimately lead to synapse and neuron loss. Although long …

Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy. Dysregulation of
glutamate transporters has been a common finding across animal models of epilepsy and in …

Hippocampal network activity is predominantly coordinated by γ-amino-butyric acid (GABA)
ergic neurons. We have previously hypothesized that the altered excitability of hippocampal …

Alzheimer's Disease (AD) and epilepsy are common neurological diseases. The prevalence
of epilepsy in AD patients is higher than in healthy subjects, but identifying the reasons for …

Introduction This study aimed to investigate the association between brain networks and
epilepsy development in patients with Alzheimer disease (AD). Methods We enrolled …

Alzheimer's disease (AD) can increase the risk of epilepsy by up to 10‐fold compared to
healthy age‐matched controls. However, the pathological mechanisms that underlie this …

Altered GABAergic inhibitory tone has been observed in association with a number of both
acute and chronic models of epilepsy and is believed to be the result, in part, of a decrease …

Increasing evidence coming from both experimental and humans' studies strongly suggest
the existence of a link between epilepsy, in particular temporal lobe epilepsy (TLE), and …