A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase
MC Myzak, PA Karplus, FL Chung, RH Dashwood - Cancer research, 2004 - AACR
Sulforaphane (SFN), a compound found at high levels in broccoli and broccoli sprouts, is a
potent inducer of phase 2 detoxification enzymes and inhibits tumorigenesis in animal …
potent inducer of phase 2 detoxification enzymes and inhibits tumorigenesis in animal …
Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects
MC Myzak, P Tong, WM Dashwood… - Experimental …, 2007 - journals.sagepub.com
Sulforaphane (SFN) is an isothiocyanate found in cruciferous vegetables such as broccoli.
This anticarcinogen was first identified as a potent inducer of Phase 2 enzymes, but …
This anticarcinogen was first identified as a potent inducer of Phase 2 enzymes, but …
Sulforaphane induces cell type–specific apoptosis in human breast cancer cell lines
A Pledgie-Tracy, MD Sobolewski, NE Davidson - Molecular cancer …, 2007 - AACR
Sulforaphane, an isothiocyanate found in cruciferous vegetables, has been shown to induce
phase 2 detoxication enzymes and inhibit the growth of chemically induced mammary …
phase 2 detoxication enzymes and inhibit the growth of chemically induced mammary …
[HTML][HTML] Sulforaphane inhibits human MCF-7 mammary cancer cell mitotic progression and tubulin polymerization
SJT Jackson, KW Singletary - The Journal of nutrition, 2004 - Elsevier
Sulforaphane (SUL), an isothiocyanate derived from hydrolysis of glucoraphanin in broccoli
and other cruciferous vegetables, was shown to induce phase II detoxification enzymes …
and other cruciferous vegetables, was shown to induce phase II detoxification enzymes …
Chemoprotection by sulforaphane: keep one eye beyond Keap1
MC Myzak, RH Dashwood - Cancer letters, 2006 - Elsevier
Sulforaphane (SFN) is an isothiocyanate found in cruciferous vegetables, with particularly
high levels detected in broccoli and broccoli sprouts. Over a decade ago, this phytochemical …
high levels detected in broccoli and broccoli sprouts. Over a decade ago, this phytochemical …
Dietary histone deacetylase inhibitors: from cells to mice to man
RH Dashwood, E Ho - Seminars in cancer biology, 2007 - Elsevier
Sulforaphane (SFN) is an isothiocyanate found in cruciferous vegetables, such as broccoli
and broccoli sprouts. This anticarcinogen was first identified as a potent inducer of Phase 2 …
and broccoli sprouts. This anticarcinogen was first identified as a potent inducer of Phase 2 …
Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells
MC Myzak, K Hardin, R Wang, RH Dashwood… - …, 2006 - academic.oup.com
Sulforaphane (SFN), an isothiocyanate first isolated from broccoli, exhibits chemopreventive
properties in prostate cancer cells through mechanisms that are poorly understood. We …
properties in prostate cancer cells through mechanisms that are poorly understood. We …
Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells
JD Clarke, A Hsu, Z Yu… - Molecular nutrition & …, 2011 - Wiley Online Library
Scope: Sulforaphane (SFN) is an isothiocyanate derived from cruciferous vegetables such
as broccoli. The ability of SFN to inhibit histone deacetylase (HDAC) enzymes may be one …
as broccoli. The ability of SFN to inhibit histone deacetylase (HDAC) enzymes may be one …
Dietary sulforaphane in cancer chemoprevention: the role of epigenetic regulation and HDAC inhibition
SM Tortorella, SG Royce, PV Licciardi… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: Sulforaphane, produced by the hydrolytic conversion of glucoraphanin after
ingestion of cruciferous vegetables, particularly broccoli and broccoli sprouts, has been …
ingestion of cruciferous vegetables, particularly broccoli and broccoli sprouts, has been …
Sulforaphane: a naturally occurring mammary carcinoma mitotic inhibitor, which disrupts tubulin polymerization
SJT Jackson, KW Singletary - Carcinogenesis, 2004 - academic.oup.com
Sulforaphane (SUL), an isothiocyanate found in broccoli and other cruciferous vegetables,
has been shown to induce phase II detoxification enzymes, inhibit chemically induced …
has been shown to induce phase II detoxification enzymes, inhibit chemically induced …