A method for genome-wide genealogy estimation for thousands of samples
Abstract Knowledge of genome-wide genealogies for thousands of individuals would
simplify most evolutionary analyses for humans and other species, but has remained …
simplify most evolutionary analyses for humans and other species, but has remained …
Bayesian inference of ancient human demography from individual genome sequences
Whole-genome sequences provide a rich source of information about human evolution.
Here we describe an effort to estimate key evolutionary parameters based on the whole …
Here we describe an effort to estimate key evolutionary parameters based on the whole …
Measurement of the human allele frequency spectrum demonstrates greater genetic drift in East Asians than in Europeans
A Keinan, JC Mullikin, N Patterson, D Reich - Nature genetics, 2007 - nature.com
Large data sets on human genetic variation have been collected recently, but their
usefulness for learning about history and natural selection has been limited by biases in the …
usefulness for learning about history and natural selection has been limited by biases in the …
Genotype, haplotype and copy-number variation in worldwide human populations
Genome-wide patterns of variation across individuals provide a powerful source of data for
uncovering the history of migration, range expansion, and adaptation of the human species …
uncovering the history of migration, range expansion, and adaptation of the human species …
Inference of human population history from individual whole-genome sequences
The history of human population size is important for understanding human evolution.
Various studies,,,, have found evidence for a founder event (bottleneck) in East Asian and …
Various studies,,,, have found evidence for a founder event (bottleneck) in East Asian and …
Biobank-scale inference of ancestral recombination graphs enables genealogical analysis of complex traits
BC Zhang, A Biddanda, ÁF Gunnarsson, F Cooper… - Nature Genetics, 2023 - nature.com
Genome-wide genealogies compactly represent the evolutionary history of a set of genomes
and inferring them from genetic data has the potential to facilitate a wide range of analyses …
and inferring them from genetic data has the potential to facilitate a wide range of analyses …
Inferring human population size and separation history from multiple genome sequences
S Schiffels, R Durbin - Nature genetics, 2014 - nature.com
The availability of complete human genome sequences from populations across the world
has given rise to new population genetic inference methods that explicitly model ancestral …
has given rise to new population genetic inference methods that explicitly model ancestral …
Human genome sequence variation and the influence of gene history, mutation and recombination
Variation in the human genome sequence is key to understanding susceptibility to disease
in modern populations and the history of ancestral populations. Unlocking this information …
in modern populations and the history of ancestral populations. Unlocking this information …
[HTML][HTML] Toward a more uniform sampling of human genetic diversity: a survey of worldwide populations by high-density genotyping
High-throughput genotyping data are useful for making inferences about human
evolutionary history. However, the populations sampled to date are unevenly distributed …
evolutionary history. However, the populations sampled to date are unevenly distributed …
[HTML][HTML] A map of human genome variation from population scale sequencing
1000 Genomes Project Consortium - Nature, 2010 - ncbi.nlm.nih.gov
Abstract The 1000 Genomes Project aims to provide a deep characterisation of human
genome sequence variation as a foundation for investigating the relationship between …
genome sequence variation as a foundation for investigating the relationship between …