Applications of deep learning in understanding gene regulation
Gene regulation is a central topic in cell biology. Advances in omics technologies and the
accumulation of omics data have provided better opportunities for gene regulation studies …
accumulation of omics data have provided better opportunities for gene regulation studies …
A hybrid deep learning framework for gene regulatory network inference from single-cell transcriptomic data
Inferring gene regulatory networks (GRNs) based on gene expression profiles is able to
provide an insight into a number of cellular phenotypes from the genomic level and reveal …
provide an insight into a number of cellular phenotypes from the genomic level and reveal …
Deep learning for regulatory genomics
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Deep learning for computational biology
Technological advances in genomics and imaging have led to an explosion of molecular
and cellular profiling data from large numbers of samples. This rapid increase in biological …
and cellular profiling data from large numbers of samples. This rapid increase in biological …
Computational biology: deep learning
Deep learning is the trendiest tool in a computational biologist's toolbox. This exciting class
of methods, based on artificial neural networks, quickly became popular due to its …
of methods, based on artificial neural networks, quickly became popular due to its …
Modeling genomic regulatory networks with big data
H Bolouri - Trends in Genetics, 2014 - cell.com
High-throughput sequencing, large-scale data generation projects, and web-based cloud
computing are changing how computational biology is performed, who performs it, and what …
computing are changing how computational biology is performed, who performs it, and what …
Recent advances of deep learning in bioinformatics and computational biology
Extracting inherent valuable knowledge from omics big data remains as a daunting problem
in bioinformatics and computational biology. Deep learning, as an emerging branch from …
in bioinformatics and computational biology. Deep learning, as an emerging branch from …
Predictive analyses of regulatory sequences with EUGENe
Deep learning has become a popular tool to study cis-regulatory function. Yet efforts to
design software for deep-learning analyses in regulatory genomics that are findable …
design software for deep-learning analyses in regulatory genomics that are findable …
Towards more realistic simulated datasets for benchmarking deep learning models in regulatory genomics
EI Prakash, A Shrikumar… - Machine Learning in …, 2022 - proceedings.mlr.press
Deep neural networks and support vector machines have been shown to accurately predict
genome-wide signals of regulatory activity from raw DNA sequences. These models are …
genome-wide signals of regulatory activity from raw DNA sequences. These models are …
A guide to machine learning for biologists
The expanding scale and inherent complexity of biological data have encouraged a growing
use of machine learning in biology to build informative and predictive models of the …
use of machine learning in biology to build informative and predictive models of the …