Background Acute respiratory distress syndrome (ARDS) is a disease with high mortality
and morbidity. Regulator of G protein signaling protein 6 (RGS6), identified as a tumor …

Regulator of G-protein signaling 10 (RGS10) is a member of the superfamily of RGS proteins
that canonically act as GTPase activating proteins (GAPs). RGS proteins accelerate GTP …

Regulator of G protein signaling 5 (RGS5) belongs to the R4 subfamily of RGS proteins, a
family of GTPase activating proteins, which is dynamically regulated in various biological …

Background Asthma exacerbations are associated with the recruitment of neutrophils to the
lungs. These cells release proteases and mediators, many of which act at G protein-coupled …

Seasonal influenza epidemics represent a significant global health threat. The exacerbated
immune response triggered by respiratory influenza virus infection causes severe …

Regulator of G-protein signaling (RGS) family members are regulatory molecules which act
as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins …

Objective To investigate the mechanism of action of Srg3 in acute lung injury caused by
sepsis. Methods First, a sepsis-induced acute lung injury rat model was established using …

T cell migration toward sites of antigen exposure is mediated by G protein signaling and is a
key function in the development of immune responses. Regulators of G protein signaling …

G protein–coupled receptors (GPCRs) are important regulators of cell functions in asthma.
We recently reported that regulator of G-protein signaling (RGS) 2, a selective modulator of …

Purpose Regulator of G-protein signaling (RGS) proteins are GTPase-activating proteins
that target the α-subunit of heterotrimeric G proteins. Many studies have shown that RGS …