The interaction between the peripheral immune system and the brain is increasingly being
recognized as an important layer of neuroimmune regulation and plays vital roles in brain …

The interaction between peripheral immune cells and the brain is an important component of
the neuroimmune axis. Unconventional T cells, which include natural killer T (NKT) cells …

The immune system is deeply involved in autoimmune diseases of the central nervous
system (CNS), such as multiple sclerosis, N-methyl-d-aspartate (NMDA) receptor …

Traumatic brain injury (TBI) leaves many survivors with long-term disabilities. A prolonged
immune response in the brain may cause neurodegeneration, resulting in chronic …

The immune system is intricately involved in brain development and physiological neuronal
function. The influence of the adaptive immune system on several brain diseases has been …

Pathogenic mechanisms of T cells in several central nervous system (CNS) disorders are
well-established. However, more recent studies have uncovered compelling beneficial roles …

CD4+ T cells orchestrate innate and adaptive immunity. In the central nervous system they
modulate immune responses including cell trafficking and glial neuroregulatory functions …

Stroke, which occurs during a loss of blood flow to the brain, is a global disease that
accounts for 10% of yearly mortality. But stroke is also a leading cause of long-term adult …

T cells within the central nervous system (CNS) have been generally considered
pathogenic, especially in the context of neuroinflammatory disease. However, recent …

CD3+ CD4− CD8− T cells (double-negative T cells; DNTs) have diverse functions in
peripheral immune-related diseases by regulating immunological and inflammatory …