Alzheimer's disease is a neurological disorder, which is the most common form of dementia
affecting mostly elderly people. The number of patients is still rapidly increasing which …

Alzheimer's Disease (AD) is one of the most common forms of dementia in elderly people.
To date, efficacious therapeutic agent for the treatment of AD is still very limited, so it has …

Alzheimer's disease (AD) is a multifactorial neurological disorder among elderly people and
combinatorial factors such as genetic, lifestyle, and environmental are involved in onset and …

A series of benzoates (or phenylacetates or cinnamates)–tacrine hybrids (7 ao) were
designed, synthesized and evaluated as multi-potent anti-Alzheimer drug candidates. The …

Alzheimer's disease (AD) is a neurodegenerative disorder, which is complex and
progressive; it has not only threatened the health of elderly people, but also burdened the …

A series of novel tacrine–cinnamate and tacrine–cinnamylidene acetate hybrids have been
designed, synthesized and evaluated as multitarget compounds for the treatment of …

Alzheimer's disease (AD) as a complicated and progressive neurodegenerative disorder is
the most common form of dementia and memory loss. On account of the multifactorial …

Background: The design of multifunctional agents represents one of the most active
research field in medicinal chemistry. In particular, tacrine, a well known …

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder. Several hallmarks
such as β-amyloid (Aβ) aggregation underlying amyloid plaque formation, Τ …

The multifactorial nature of Alzheimer's disease (AD) offers us a textbook example where
parental compounds, mostly marketed, are modified with the aim of improving and/or …