New strategies in prostate cancer: prostate-specific membrane antigen (PSMA) ligands for diagnosis and therapy

U Haberkorn, M Eder, K Kopka, JW Babich… - Clinical Cancer …, 2016 - AACR
Key issues for prostate cancer patients are the detection of recurrent disease and the
treatment of metastasized cancer. Early detection is a major challenge for all conventional …

[HTML][HTML] PSMA theranostics: review of the current status of PSMA-targeted imaging and radioligand therapy

W Jones, K Griffiths, PC Barata, CJ Paller - Cancers, 2020 - mdpi.com
Prostate-specific membrane antigen (PSMA) has been the subject of extensive investigation
in the past two decades as a promising molecular target for prostate cancer (PCa). Its …

PSMA theranostics: current status and future directions

K Rahbar, A Afshar-Oromieh, H Jadvar… - Molecular …, 2018 - journals.sagepub.com
Prostate-specific membrane antigen (PSMA) is a promising target for imaging diagnostics
and targeted radionuclide therapy (theranostics) of prostate cancer and its metastases …

[HTML][HTML] PSMA theranostics: current landscape and future outlook

H Zhang, S Koumna, F Pouliot, JM Beauregard… - Cancers, 2021 - mdpi.com
Simple Summary The prognosis for metastatic prostate cancer patients remains poor.
Prostate-specific membrane antigen (PSMA) is overexpressed in prostate cancer and is a …

[HTML][HTML] Targeting PSMA revolutionizes the role of nuclear medicine in diagnosis and treatment of prostate cancer

WI Luining, MCF Cysouw, D Meijer, NH Hendrikse… - Cancers, 2022 - mdpi.com
Simple Summary Imaging plays a crucial role in the accurate staging of prostate cancer.
Prostate-specific membrane antigen (PSMA) is overexpressed in prostate cancer cells, and …

[HTML][HTML] Prostate specific membrane antigen—a target for imaging and therapy with radionuclides

K Bouchelouche, PL Choyke, J Capala - Discovery medicine, 2010 - ncbi.nlm.nih.gov
Prostate cancer continues to represent a major health problem, and yet there is no effective
treatment available for advanced metastatic disease. Thus, there is an urgent need for the …

[HTML][HTML] PSMA-targeting radiopharmaceuticals for prostate cancer therapy: recent developments and future perspectives

M El Fakiri, NM Geis, N Ayada, M Eder, AC Eder - Cancers, 2021 - mdpi.com
Simple Summary One of the most frequently diagnosed cancer in men is adenocarcinoma of
the prostate. Once the disease is metastatic, only very limited treatment options are …

[HTML][HTML] Targeted α-therapy of prostate cancer using radiolabeled PSMA inhibitors: a game changer in nuclear medicine

R Chakravarty, CM Siamof, A Dash… - American journal of …, 2018 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is one of the most common malignancies in men and is a major
contributor to cancer related deaths worldwide. Metastatic spread and disease progression …

[HTML][HTML] PSMA radioligand therapy for solid tumors other than prostate cancer: background, opportunities, challenges, and first clinical reports

MJM Uijen, YHW Derks, RIJ Merkx… - European journal of …, 2021 - Springer
In the past decade, a growing body of literature has reported promising results for prostate-
specific membrane antigen (PSMA)-targeted radionuclide imaging and therapy in prostate …

Theranostics of prostate cancer: from molecular imaging to precision molecular radiotherapy targeting the prostate specific membrane antigen

HR Kulkarni, A Singh, T Langbein… - The British journal of …, 2018 - academic.oup.com
Alterations at the molecular level are a hallmark of cancer. Prostate cancer is associated
with the overexpression of prostate-specific membrane antigen (PSMA) in a majority of …