Hypovitaminosis D exacerbates the DNA damage load in human uterine fibroids, which is ameliorated by vitamin D3 treatment
Uterine fibroids (UFs) are the most common benign neoplastic threat to women's health and
associated with DNA damage and genomic instability. Hypovitaminosis D is a known risk …
associated with DNA damage and genomic instability. Hypovitaminosis D is a known risk …
Diet-induced vitamin D deficiency triggers inflammation and DNA damage profile in murine myometrium
H ElHusseini, H Elkafas, M Abdelaziz… - … journal of women's …, 2018 - Taylor & Francis
Background Previously, we reported a significantly higher prevalence of uterine fibroids
(UFs) in African American women. This minority group also commonly suffers from vitamin D …
(UFs) in African American women. This minority group also commonly suffers from vitamin D …
Vitamin D: mechanism of action and biological effects in uterine fibroids
Uterine fibroids (UFs) are the most common benign gynecological tumors. It was estimated
that fifty percent of women presenting with UFs has symptomatology that negatively …
that fifty percent of women presenting with UFs has symptomatology that negatively …
Endocrine-disrupting chemicals and Vitamin D deficiency in the pathogenesis of uterine fibroids
H Elkafas, OA Badary, E Elmorsy, R Kamel… - Journal of advanced …, 2021 - journals.ekb.eg
Uterine fibroids (UFs) are the most prevalent gynecologic neoplasm, affecting 70–80% of
women over their lifespan. Although UFs are benign, they can become life-threatening and …
women over their lifespan. Although UFs are benign, they can become life-threatening and …
Vitamin D, a promising natural compound with anti-uterine fibroid characteristics
Uterine fibroids (UFs; leiomyomas) are benign monoclonal neoplasms of the myometrium
and represent the most common tumors in reproductive-age women worldwide. Tumors …
and represent the most common tumors in reproductive-age women worldwide. Tumors …
Vitamin D3 ameliorates DNA damage caused by developmental exposure to endocrine disruptors in the uterine myometrial stem cells of eker rats
Early-life exposure of the myometrium to endocrine-disrupting chemicals (EDCs) has been
shown to increase the risk of uterine fibroid (UF) prevalence in adulthood. Vitamin D3 …
shown to increase the risk of uterine fibroid (UF) prevalence in adulthood. Vitamin D3 …
A systematic review of vitamin D and fibroids: pathophysiology, prevention, and treatment
Uterine fibroids are the most common tumor of reproductive-age women worldwide and
cause significant morbidity in affected women. Vitamin D has emerged as a potential therapy …
cause significant morbidity in affected women. Vitamin D has emerged as a potential therapy …
The significance of measuring vitamin D serum levels in women with uterine fibroids
M Ciebiera, M Ali, L Prince, S Zgliczyński, G Jakiel… - Reproductive …, 2021 - Springer
Uterine fibroids (UFs) are benign tumors originating from smooth muscle cells and are
considered a common pathology that affects numerous women which is a notable socio …
considered a common pathology that affects numerous women which is a notable socio …
Vitamin D and uterine fibroids—review of the literature and novel concepts
M Ciebiera, M Włodarczyk, M Ciebiera… - International Journal of …, 2018 - mdpi.com
This article provides a detailed review of current knowledge on the role of vitamin D and its
receptor in the biology and management of uterine fibroids (UFs). Authors present ideas for …
receptor in the biology and management of uterine fibroids (UFs). Authors present ideas for …
[HTML][HTML] Role of vitamin D in uterine fibroid biology
S Brakta, JS Diamond, A Al-Hendy, MP Diamond… - Fertility and sterility, 2015 - Elsevier
Objective To provide a detailed summary of current scientific knowledge on uterine fibroids
(leiomyomas) in vitro and in in vivo animal models, as well as to postulate the potential role …
(leiomyomas) in vitro and in in vivo animal models, as well as to postulate the potential role …