Lipid abnormalities are among the key risk factors for cardiovascular disease. Indeed, lipid-
modifying drugs—in particular, the statins, which primarily lower plasma levels of low …

Low levels of HDL cholesterol are a significant predictor of atherosclerotic cardiovascular
events. HDL is believed to protect against atherosclerosis by promoting reverse cholesterol …

Low-density lipoproteins (LDL) are atherogenic and represent a strong cardiovascular risk
factor. Therefore, LDL-cholesterol (LDL-C) remains the primary target in lipid lowering …

The cholesterol concentrations of low-density lipoprotein (LDL) and high-density lipoprotein
(HDL) have traditionally served as risk factors for cardiovascular disease. As such, novel …

HDL-cholesterol and cardiovascular disease: rethinking our a... : Current Opinion in
Cardiology HDL-cholesterol and cardiovascular disease: rethinking our approach : Current …

Innovative pharmacological approaches to raise anti-atherogenic high-density lipoprotein-
cholesterol (HDL-C) are currently of considerable interest, particularly in atherogenic …

There is a large body of evidence demonstrating an inverse correlation between circulating
levels of high-density lipoprotein (HDL) cholesterol and cardiovascular disease risk. For …

Coronary heart disease remains a major cause of worldwide morbidity and mortality despite
therapeutic advances that control many risk factors such as low-density lipoprotein …

High‐density‐lipoprotein cholesterol (HDL‐C) has been identified in population studies as
an independent inverse predictor of cardiovascular events. Although the causal nature of …

Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …