Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease
Background Statins are a class of medications that reduce cholesterol by inhibiting 3-
hydroxy-3-methylglutaryl-coenzyme A reductase. Whether statins can benefit patients with …
hydroxy-3-methylglutaryl-coenzyme A reductase. Whether statins can benefit patients with …
Statin use and the risk of incident dementia: the Cardiovascular Health Study
Background Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) reduce
cardiovascular risk through mechanisms that might affect the development of dementia …
cardiovascular risk through mechanisms that might affect the development of dementia …
Statins in the prevention of dementia and Alzheimer's disease: a meta‐analysis of observational studies and an assessment of confounding
WB Wong, VW Lin, D Boudreau… - … and drug safety, 2013 - Wiley Online Library
Background Studies demonstrate the potential for statins to prevent dementia and
Alzheimer's disease (AD), but the evidence is inconclusive. Objective Conduct a meta …
Alzheimer's disease (AD), but the evidence is inconclusive. Objective Conduct a meta …
Association between use of statin and risk of dementia: a meta-analysis of observational studies
Abstract Background and Aims: The impact of statin on dementia risk reduction has been a
subject of debate over the last decade, but the evidence remains inconclusive. Therefore …
subject of debate over the last decade, but the evidence remains inconclusive. Therefore …
Statins use and risk of dementia: A dose–response meta analysis
X Zhang, J Wen, Z Zhang - Medicine, 2018 - journals.lww.com
Previous studies have indicated that statins use is associated with risk of dementia, but
presented controversial results. Medline, Embase, Web of Science, and the Cochrane …
presented controversial results. Medline, Embase, Web of Science, and the Cochrane …
Prevention and treatment of dementia or Alzheimer's disease by statins: a meta-analysis
B Zhou, S Teramukai, M Fukushima - Dementia and geriatric cognitive …, 2007 - karger.com
Abstract Background/Aim: 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors
(statins) are thought to reduce the amount of Abeta peptides by reducing cholesterol from …
(statins) are thought to reduce the amount of Abeta peptides by reducing cholesterol from …
The impact of the use of statins on the prevalence of dementia and the progression of cognitive impairment
I Hajjar, J Schumpert, V Hirth, D Wieland… - The Journals of …, 2002 - academic.oup.com
Background. Previous evidence suggests that treatment with 3-hydroxy-3-methylglutaryl-
coenzyme-A reductase inhibitors (statins) has a positive impact on dementia. We decided to …
coenzyme-A reductase inhibitors (statins) has a positive impact on dementia. We decided to …
Statin therapy and risk of Alzheimer's and age‐related neurodegenerative diseases
G Torrandell‐Haro, GL Branigan, F Vitali… - … Research & Clinical …, 2020 - Wiley Online Library
Introduction Establishing efficacy of and molecular pathways for statins has the potential to
impact incidence of Alzheimer's and age‐related neurodegenerative diseases (NDD) …
impact incidence of Alzheimer's and age‐related neurodegenerative diseases (NDD) …
Use of statins and the risk of dementia and mild cognitive impairment: A systematic review and meta-analysis
We conducted a systematic review and meta-analysis to investigate whether the use of
statins could be associated with the risk of all-caused dementia, Alzheimer's disease (AD) …
statins could be associated with the risk of all-caused dementia, Alzheimer's disease (AD) …
Sex and race differences in the association between statin use and the incidence of Alzheimer disease
Importance To our knowledge, no effective treatments exist for Alzheimer disease, and new
molecules are years away. However, several drugs prescribed for other conditions have …
molecules are years away. However, several drugs prescribed for other conditions have …