Unreliable mtDNA data due to nuclear insertions: a cautionary tale from analysis of humans and other great apes

O Thalmann, J Hebler, HN Poinar, S Pääbo… - Molecular …, 2004 - Wiley Online Library
Abstract Analysis of mitochondrial DNA sequence variation has been used extensively to
study the evolutionary relationships of individuals and populations, both within and across …

Determination of mitochondrial genetic diversity in mammals

B Nabholz, JF Mauffrey, E Bazin, N Galtier, S Glemin - Genetics, 2008 - academic.oup.com
Mitochondrial DNA (mtDNA) is one of the most popular population genetic markers. Its
relevance as an indicator of population size and history has recently been questioned by …

Large variation in the ratio of mitochondrial to nuclear mutation rate across animals: implications for genetic diversity and the use of mitochondrial DNA as a molecular …

R Allio, S Donega, N Galtier… - Molecular biology and …, 2017 - academic.oup.com
It is commonly assumed that mitochondrial DNA (mtDNA) evolves at a faster rate than
nuclear DNA (nuDNA) in animals. This has contributed to the popularity of mtDNA as a …

Does nonneutral evolution shape observed patterns of DNA variation in animal mitochondrial genomes?

AS Gerber, R Loggins, S Kumar… - Annual review of …, 2001 - annualreviews.org
▪ Abstract Early studies of animal mitochondrial DNA (mtDNA) assumed that nucleotide
sequence variation was neutral. Recent analyses of sequences from a variety of taxa have …

What is mtDNA good for in the study of primate evolution?

DJ Melnick, GA Hoelzer - Evolutionary Anthropology: Issues …, 1993 - Wiley Online Library
Recombinant DNA methods have made accessible the nuclear and organelle genomes of a
vast array of plant and animal species. 1–3 Although evolutionary biologists and …

The occurrence, detection, and avoidance of mitochondrial DNA translocations in mammalian systematics and phylogeography

DA Triant, JA DeWoody - Journal of Mammalogy, 2007 - academic.oup.com
The generation and analysis of mitochondrial DNA (mtDNA) sequence data has become
routine in mammalogy. Unfortunately, these analyses can be confounded because …

Animal mitochondrial DNA as a genetic marker in population and evolutionary biology

RG Harrison - Trends in Ecology & Evolution, 1989 - Elsevier
Animal mitochondrial DNA (mtDNA) is playing an increasingly important role as a genetic
marker in population and evolutionary biology. The popularity of this molecule derives, in …

The biogeography of mitochondrial and nuclear discordance in animals

DPL Toews, A Brelsford - Molecular ecology, 2012 - Wiley Online Library
Combining nuclear (nuDNA) and mitochondrial DNA (mtDNA) markers has improved the
power of molecular data to test phylogenetic and phylogeographic hypotheses and has …

Evolution of animal mitochondrial DNA: relevance for population biology and systematics

C Moritz, TE Dowling, WM Brown - Annual review of ecology and …, 1987 - JSTOR
In the past decade, mitochondrial DNA (mtDNA) analysis has become es-tablished as a
powerful tool for evolutionary studies of animals. These studies, recently reviewed by Avise …

Nuclear insertions help and hinder inference of the evolutionary history of gorilla mtDNA

O Thalmann, D Serre, M Hofreiter, D Lukas… - Molecular …, 2005 - Wiley Online Library
Numts are fragments of mitochondrial DNA (mtDNA) that have been translocated to the
nucleus, where they can persist while their mitochondrial counterparts continue to rapidly …