Oxidative stress, characterized by excessive accumulation of reactive oxygen species
(ROS), is involved in acute myocardial infarction (AMI)-related pathological processes and …

A challenge in treating cardiac injury is the low heart-specificity of the drugs. Nanostructured
lipid carriers (NLCs) are a relatively new format of lipid nanoparticles which have been used …

Mitochondrial dysfunction of cardiomyocytes (CMs) has been identified as a significant
pathogenesis of early myocardial infarction (MI). However, only a few agents or strategies …

Some gel types have been reported to prevent left ventricular (LV) remodeling in myocardial
infarction (MI) animal models. In this study, we tested biodegradable thermoresponsive gels …

Congestive heart failure is mostly resulted in a consequence of the limited myocardial
regeneration capacity after acute myocardial infarction. Targeted delivery of proangiogenic …

Abstract Poly-lactide-co-glycolide (PLGA) microparticles emerged as one of the most
promising strategies to achieve site-specific drug delivery. Although these microparticles …

Electrospun nanofibrous sheets get increasing attention in myocardial infarction (MI)
treatment due to their good cytocompatibility to deliver transplanted stem cells to infarcted …

Heart tissue engineering is critical in the treatment of myocardial infarction, which may
benefit from drug-releasing smart materials. In this study, we load a small molecule (3i-1000) …

Cardiovascular diseases such as myocardial infarction (MI) are among the major causes of
death worldwide. Although intramyocardial injection of hydrogels can effectively enhance …

Microgrooved thin PLGA film (≈ 30 μm) is successfully fabricated on a Teflon mold, which
could be readily peeled off and is used for the construction of a biomimetic cardiac patch …