Exercise enhances insulin sensitivity; it also improves adipocyte metabolism and reduces
adipose tissue inflammation through poorly defined mechanisms. Fibroblast growth factor 21 …

Objective The protective effects of exercise against glucose dysmetabolism have been
generally reported. However, the mechanism by which exercise improves glucose …

Fibroblast growth factor 21 (FGF21) plays an important role in the regulation of energy
homeostasis during starvation and has an excellent therapeutic potential for the treatment of …

Fibroblast growth factor 21 (FGF-21) is a protein that is involved in the regulation of glucose,
lipids, and energy metabolism. To act on target tissues, endocrine FGF-21 binds preferably …

Exercise promotes adipose remodeling and improves obesity-induced metabolic disorders
through mechanisms that remain obscure. Here, we identify the FGF21 signaling in adipose …

Background and aim Fibroblast growth factor 21 (FGF21) is positively associated with body
mass index, potentially as a compensatory mechanism to mediate obesity related metabolic …

Previous studies reveal that fibroblast growth factor 21 (FGF21) sensitizes insulin to achieve
a synergy in regulating glucose metabolism. Here, we report that insulin sensitizes FGF21 in …

Objective Obesity‐related, chronic, low‐grade inflammation has been identified as a key
factor in the development of many metabolic diseases, such as type 2 diabetes and …

Fibroblast growth factor 21 (FGF21) is an emerging regulator of local and systemic metabolic
homeostasis. Treatment with pharmacological levels of FGF21 alleviates obesity and …

FGF21 is an endocrine hormone that regulates energy homeostasis and insulin sensitivity.
The mechanism of FGF21 action and the tissues responsible for these effects have been …