Bacterial terpenome

JD Rudolf, TA Alsup, B Xu, Z Li - Natural product reports, 2021 - pubs.rsc.org
Covering: up to mid-2020 Terpenoids, also called isoprenoids, are the largest and most
structurally diverse family of natural products. Found in all domains of life, there are over 80 …

Exploration and mining of the bacterial terpenome

DE Cane, H Ikeda - Accounts of chemical research, 2012 - ACS Publications
Tens of thousands of terpenoids are present in both terrestrial and marine plants, as well as
fungi. In the last 5–10 years, however, it has become evident that terpenes are also …

Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering

EJN Helfrich, GM Lin, CA Voigt… - Beilstein journal of …, 2019 - beilstein-journals.org
Terpenoids are the largest and structurally most diverse class of natural products. They
possess potent and specific biological activity in multiple assays and against diseases …

Widespread biosynthesis of 16-carbon terpenoids in bacteria

YT Duan, A Koutsaviti, M Harizani, C Ignea… - Nature Chemical …, 2023 - nature.com
Terpenoids are the most diverse group of specialized metabolites with numerous
applications. Their biosynthesis is based on the five-carbon isoprene building block and, as …

Microbial Platform for Terpenoid Production: Escherichia coli and Yeast

C Wang, M Liwei, JB Park, SH Jeong, G Wei… - Frontiers in …, 2018 - frontiersin.org
Terpenoids, also called isoprenoids, are a large and highly diverse family of natural
products with important medical and industrial properties. However, a limited production of …

Terpene synthases are widely distributed in bacteria

Y Yamada, T Kuzuyama, M Komatsu… - Proceedings of the …, 2015 - National Acad Sciences
Odoriferous terpene metabolites of bacterial origin have been known for many years. In
genome-sequenced Streptomycetaceae microorganisms, the vast majority produces the …

Biosynthesis, evolution and ecology of microbial terpenoids

M Avalos, P Garbeva, L Vader, GP van Wezel… - Natural Product …, 2022 - pubs.rsc.org
Covering: through June 2021 Terpenoids are the largest class of natural products
recognised to date. While mostly known to humans as bioactive plant metabolites and part of …

Toward improved terpenoids biosynthesis: strategies to enhance the capabilities of cell factories

E Fordjour, EO Mensah, Y Hao, Y Yang, X Liu… - Bioresources and …, 2022 - Springer
Terpenoids form the most diversified class of natural products, which have gained
application in the pharmaceutical, food, transportation, and fine and bulk chemical …

New frontiers: harnessing pivotal advances in microbial engineering for the biosynthesis of plant-derived terpenoids

MS Belcher, J Mahinthakumar, JD Keasling - Current opinion in …, 2020 - Elsevier
Highlights•Terpenoids are a vast and diverse class of compounds with applications in both
the industrial and human health spaces.•Computational biology and gene discovery enable …

Exploring novel bacterial terpene synthases

GK Reddy, NGH Leferink, M Umemura, ST Ahmed… - PloS one, 2020 - journals.plos.org
Terpenes are the largest class of natural products with extensive structural diversity and are
widely used as pharmaceuticals, herbicides, flavourings, fragrances, and biofuels. While …