Gamma-aminobutyric acid A receptor, α-2 (GABRA2) variants as individual markers for alcoholism: a meta-analysis

E Zintzaras - Psychiatric genetics, 2012 - journals.lww.com
Objectives The available evidence from the genetic association studies (GAS) published to
date on the association between variants in the GABRA2 gene and alcoholism has …

Association of gamma-aminobutyric acid A receptor α2 gene (GABRA2) with alcohol use disorder

D Li, A Sulovari, C Cheng, H Zhao… - …, 2014 - nature.com
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter in mammalian
brain. GABA receptor are involved in a number of complex disorders, including substance …

Confirmation of association of the GABRA2 gene with alcohol dependence by subtype-specific analysis

C Fehr, T Sander, A Tadic, KP Lenzen… - Psychiatric …, 2006 - journals.lww.com
Objectives Three recent studies revealed a haplotypic association of alcohol dependence
with the gene encoding the α 2 subunit of the γ-aminobutyric acid type A (GABA A) receptor …

GABA-A2 receptor subunit gene (GABRA2) polymorphisms and risk for alcohol dependence

M Soyka, UW Preuss, V Hesselbrock, P Zill… - Journal of psychiatric …, 2008 - Elsevier
Gamma-aminobutyric acid (GABA) A receptors are believed to mediate some of the
physiological and behavioral actions of ethanol. Recent studies have suggested that genetic …

The role of the GABRA2 polymorphism in multiplex alcohol dependence families with minimal comorbidity: within-family association and linkage analyses

AG Matthews, EK Hoffman, N Zezza, S Stiffler… - Journal of Studies on …, 2007 - jsad.com
Objective: The genes encoding the γ-aminobutyric acidA (GABAA) receptor have been the
focus of several recent studies investigating the genetic etiology of alcohol dependence …

Association between alcoholism and γ‐amino butyric acid α2 receptor subtype in a Russian population

J Lappalainen, E Krupitsky, M Remizov… - Alcoholism: Clinical …, 2005 - Wiley Online Library
Background: Two recent large genetic studies in the US population have reported
association between genetic variation in γ‐amino butyric acid α2 receptor subtype …

The Role of GABRA2 in Alcohol Dependence, Smoking, and Illicit Drug Use in an Australian Population Sample

PA Lind, S Macgregor, A Agrawal… - Alcoholism: Clinical …, 2008 - Wiley Online Library
Background: Multiple studies have shown that genetic variation in the α‐2 subunit of the
gamma‐aminobutyric acid type A (GABAA) receptor (GABRA2) is associated with risk for …

Association Analysis of Sequence Variants of the GABAAα6, β2, and γ2 Gene Cluster and Alcohol Dependence

T Sander, D Ball, R Murray, J Patel… - Alcoholism: Clinical …, 1999 - Wiley Online Library
Quantitative trait analyses in mice suggest a vulnerability locus for physiological alcohol
withdrawal severity on a chromosomal segment that harbors the genes encoding the α1, α6 …

Association of GABAA receptor α2 subunit gene (GABRA2) with alcohol dependence-related aggressive behavior

DS Strac, GN Erjavec, MN Perkovic, KN Sviglin… - Progress in neuro …, 2015 - Elsevier
Alcohol dependence is a common chronic disorder precipitated by the complex interaction
between biological, genetic and environmental risk factors. Recent studies have …

Genetic variation in GABRβ1 and the risk for developing alcohol dependence

WA McCabe, MJ Way, K Ruparelia, S Knapp… - Psychiatric …, 2017 - journals.lww.com
Associations between the γ-aminobutyric acid type-A receptors (GABA A) and alcohol
dependence risk have been reported, although the receptor subunit driving the association …