Purpose: Corneal perforation is a clinical emergency that can result in blindness. Currently
corneal perforations are treated either by cyanoacrylate glue which is toxic to corneal cells …

Purpose: To develop a human platelet lysate (hPL)–based bioink that is transparent and
also encompasses the regenerative properties of hPL to facilitate wound healing. Methods …

Purpose: To describe the use of collagen-based alternatives to cyanoacrylate glue for the
sealing of acute corneal perforations. Methods: A collagen analog comprising a collagen …

Featured Application This novel chitosan film sealant is capable of closing penetrating
corneal wounds after routine cataract surgeries, closing traumatic corneal lacerations from …

Current strategies to address corneal surface defects are insufficient to successfully resolve
damage caused by injury and/or disease. To address this issue, we have developed an …

Purpose: Acute corneal perforations need rapid closure to avoid intraocular infections or
suprachoroidal bleeding. The worldwide lack of donor corneas delays the emergency …

The current treatments for the management of corneal and scleral perforations include
sutures and adhesives. While sutures are invasive, induce astigmatism and carry a risk of …

OBJECTIVE: To compare the efficacy of fibrin glue and N-butyl-2-cyanoacrylate in corneal
perforations. DESIGN: Randomized, controlled clinical trial. PARTICIPANTS: Forty-one …

Introduction: This study was conducted to characterize morphological and functional
outcome of application of tissue adhesive (TA) in corneal perforations. Methods: This is a …

Purpose: To evaluate long-term in vivo functionality of corneas regenerated using a cell-free,
liquid hydrogel filler (LiQD Cornea) after deep corneal trauma in the feline model. Methods …