Bond-selective intensity diffraction tomography
Recovering molecular information remains a grand challenge in the widely used
holographic and computational imaging technologies. To address this challenge, we …
holographic and computational imaging technologies. To address this challenge, we …
Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy
Amyloid proteins are associated with a broad spectrum of neurodegenerative diseases.
However, it remains a grand challenge to extract molecular structure information from …
However, it remains a grand challenge to extract molecular structure information from …
[HTML][HTML] Deep image restoration for infrared photothermal heterodyne imaging
S Zhang, K Kniazev, IM Pavlovetc, S Zhang… - The Journal of …, 2021 - pubs.aip.org
Infrared photothermal heterodyne imaging (IR-PHI) is an all-optical table top approach that
enables super-resolution mid-infrared microscopy and spectroscopy. The underlying …
enables super-resolution mid-infrared microscopy and spectroscopy. The underlying …
Depth-resolved mid-infrared photothermal imaging of living cells and organisms with submicrometer spatial resolution
Chemical contrast has long been sought for label-free visualization of biomolecules and
materials in complex living systems. Although infrared spectroscopic imaging has come a …
materials in complex living systems. Although infrared spectroscopic imaging has come a …
Infrared spectroscopic laser scanning confocal microscopy for whole-slide chemical imaging
Chemical imaging, especially mid-infrared spectroscopic microscopy, enables label-free
biomedical analyses while achieving expansive molecular sensitivity. However, its slow …
biomedical analyses while achieving expansive molecular sensitivity. However, its slow …
High-speed in vitro intensity diffraction tomography
We demonstrate a label-free, scan-free intensity diffraction tomography technique utilizing
annular illumination (aIDT) to rapidly characterize large-volume three-dimensional (3-D) …
annular illumination (aIDT) to rapidly characterize large-volume three-dimensional (3-D) …
High-throughput intensity diffraction tomography with a computational microscope
We demonstrate a motion-free intensity diffraction tomography technique that enables the
direct inversion of 3D phase and absorption from intensity-only measurements for weakly …
direct inversion of 3D phase and absorption from intensity-only measurements for weakly …
Ultrafast chemical imaging by widefield photothermal sensing of infrared absorption
Infrared (IR) imaging has become a viable tool for visualizing various chemical bonds in a
specimen. The performance, however, is limited in terms of spatial resolution and imaging …
specimen. The performance, however, is limited in terms of spatial resolution and imaging …
Resolution-enhanced intensity diffraction tomography in high numerical aperture label-free microscopy
We propose label-free and motion-free resolution-enhanced intensity diffraction tomography
(reIDT) recovering the 3D complex refractive index distribution of an object. By combining an …
(reIDT) recovering the 3D complex refractive index distribution of an object. By combining an …
Nanosecond-resolution photothermal dynamic imaging via MHZ digitization and match filtering
Photothermal microscopy has enabled highly sensitive label-free imaging of absorbers, from
metallic nanoparticles to chemical bonds. Photothermal signals are conventionally detected …
metallic nanoparticles to chemical bonds. Photothermal signals are conventionally detected …