[HTML][HTML] Extracellular matrix, regional heterogeneity of the aorta, and aortic aneurysm
Aortic aneurysm is an asymptomatic disease with dire outcomes if undiagnosed. Aortic
aneurysm rupture is a significant cause of death worldwide. To date, surgical repair or …
aneurysm rupture is a significant cause of death worldwide. To date, surgical repair or …
[HTML][HTML] Regional heterogeneity within the aorta: relevance to aneurysm disease
JM Ruddy, JA Jones, FG Spinale… - The Journal of thoracic and …, 2008 - Elsevier
Vascular remodeling within the aorta results in a loss of structural integrity with consequent
aneurysm formation. This degradation is more common in the abdominal aorta but also …
aneurysm formation. This degradation is more common in the abdominal aorta but also …
[HTML][HTML] Role of extracellular matrix and inflammation in abdominal aortic aneurysm
KL Stepien, K Bajdak-Rusinek, A Fus-Kujawa… - International journal of …, 2022 - mdpi.com
Abdominal aortic aneurysm (AAA) is one of the most dangerous cardiovascular diseases,
occurring mainly in men over the age of 55 years. As it is asymptomatic, patients are …
occurring mainly in men over the age of 55 years. As it is asymptomatic, patients are …
[HTML][HTML] Aortic aneurysms: current pathogenesis and therapeutic targets
MJ Cho, MR Lee, JG Park - Experimental & Molecular Medicine, 2023 - nature.com
Aortic aneurysm is a chronic disease characterized by localized expansion of the aorta,
including the ascending aorta, arch, descending aorta, and abdominal aorta. Although aortic …
including the ascending aorta, arch, descending aorta, and abdominal aorta. Although aortic …
[HTML][HTML] Extracellular matrix in aging aorta
A Mammoto, K Matus, T Mammoto - Frontiers in Cell and …, 2022 - frontiersin.org
The aging population is booming all over the world and arterial aging causes various age-
associated pathologies such as cardiovascular diseases (CVDs). The aorta is the largest …
associated pathologies such as cardiovascular diseases (CVDs). The aorta is the largest …
Monocytes and macrophages in abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) is a life-threatening disease associated with high
morbidity, and high mortality in the event of aortic rupture. Major advances in open surgical …
morbidity, and high mortality in the event of aortic rupture. Major advances in open surgical …
Vascular smooth muscle cells in aortic aneurysm: from genetics to mechanisms
Aortic aneurysm, including thoracic aortic aneurysm and abdominal aortic aneurysm, is the
second most prevalent aortic disease following atherosclerosis, representing the ninth …
second most prevalent aortic disease following atherosclerosis, representing the ninth …
[HTML][HTML] Endothelial dysfunction in the pathogenesis of abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA), defined as a focal dilation of the abdominal aorta beyond
50% of its normal diameter, is a common and potentially life-threatening vascular disease …
50% of its normal diameter, is a common and potentially life-threatening vascular disease …
Cellular mechanisms of aortic aneurysm formation
RA Quintana, WR Taylor - Circulation Research, 2019 - Am Heart Assoc
Aortic aneurysms are a common vascular disease in Western populations that can involve
virtually any portion of the aorta. Abdominal aortic aneurysms are much more common than …
virtually any portion of the aorta. Abdominal aortic aneurysms are much more common than …
[HTML][HTML] New insight in aetiopathogenesis of aortic diseases
E Allaire, F Schneider, F Saucy, J Dai… - European Journal of …, 2009 - Elsevier
BACKGROUND: Knowledge in the aetiopathogeny of aortic disease helps to characterise
aortic lesions better and determine the risk of evolution and therapeutic strategies as well …
aortic lesions better and determine the risk of evolution and therapeutic strategies as well …