Coat proteins of necroviruses target 14-3-3a to subvert MAPKKKα-mediated antiviral immunity in plants

Z Gao, D Zhang, X Wang, X Zhang, Z Wen… - Nature …, 2022 - nature.com
Mitogen-activated protein kinase (MAPK) cascades play an important role in innate immunity
against various pathogens in plants and animals. However, we know very little about the …

MAPKs trigger antiviral immunity by directly phosphorylating a rhabdovirus nucleoprotein in plants and insect vectors

ZH Ding, Q Gao, X Tong, WY Xu, L Ma, ZJ Zhang… - The Plant …, 2022 - academic.oup.com
Signaling by the evolutionarily conserved mitogen-activated protein kinase or extracellular
signal-regulated kinase (MAPK/ERK) plays critical roles in converting extracellular stimuli …

βC1 protein encoded in geminivirus satellite concertedly targets MKK2 and MPK4 to counter host defense

T Hu, C Huang, Y He, C Castillo-González, X Gui… - PLoS …, 2019 - journals.plos.org
Plant viruses have evolved multiple strategies to overcome host defense to establish an
infection. Here, we identified two components of a host mitogen-activated protein kinase …

The MAPK kinase kinase GmMEKK1 regulates cell death and defense responses

HY Xu, C Zhang, ZC Li, ZR Wang, XX Jiang… - Plant …, 2018 - academic.oup.com
MAPK signaling pathways play critical roles in plant immunity. Here, we silenced multiple
genes encoding MAPKs using virus-induced gene silencing mediated by Bean pod mottle …

NPK1, an MEKK1-like mitogen-activated protein kinase kinase kinase, regulates innate immunity and development in plants

H Jin, MJ Axtell, D Dahlbeck, O Ekwenna, S Zhang… - Developmental cell, 2002 - cell.com
Mitogen-activated protein kinase (MAPK) cascades are rapidly activated upon plant
recognition of invading pathogens. Here, we describe the use of virus-induced gene …

The C4 protein encoded by Tomato leaf curl Yunnan virus interferes with mitogen‐activated protein kinase cascade‐related defense responses through inhibiting the …

Y Mei, Y Wang, T Hu, Z He, X Zhou - New Phytologist, 2021 - search.ebscohost.com
Mitogen‐activated protein kinase (MAPK) cascades are involved in host defense against
pathogens and are often activated by upstream plasma membrane leucine‐rich repeat …

MAPKKKα is a positive regulator of cell death associated with both plant immunity and disease

O del Pozo, KF Pedley, GB Martin - The EMBO journal, 2004 - embopress.org
Many plant pathogens cause disease symptoms that manifest over days as regions of
localized cell death. Localized cell death (the hypersensitive response; HR) also occurs in …

Identification of three MAPKKKs forming a linear signaling pathway leading to programmed cell death in Nicotiana benthamiana

M Hashimoto, K Komatsu, K Maejima, Y Okano… - BMC plant biology, 2012 - Springer
Background The mitogen-activated protein kinase (MAPK) cascade is an evolutionarily
ancient mechanism of signal transduction found in eukaryotic cells. In plants, MAPK …

Divergent symptoms caused by geminivirus-encoded C4 proteins correlate with their ability to bind NbSKη

Y Mei, F Zhang, M Wang, F Li, Y Wang… - Journal of …, 2020 - Am Soc Microbiol
Geminiviruses induce severe developmental abnormalities in plants. The C4/AC4 protein
encoded by geminiviruses, especially those not associated with betasatellites, functions as a …

Mimic phosphorylation of a βC1 protein encoded by TYLCCNB impairs its functions as a viral suppressor of RNA silencing and a symptom determinant

X Zhong, ZQ Wang, R Xiao, L Cao, Y Wang… - Journal of …, 2017 - Am Soc Microbiol
Phosphorylation of the βC1 protein encoded by the betasatellite of tomato yellow leaf curl
China virus (TYLCCNB-βC1) by SNF1-related protein kinase 1 (SnRK1) plays a critical role …