Human pregnancy‐associated malaria‐specific B cells target polymorphic, conformational epitopes in VAR2CSA: This article became available OnlineOpen after it …

L Barfod, NL Bernasconi, M Dahlbäck… - Molecular …, 2007 - Wiley Online Library
Pregnancy‐associated malaria (PAM) is caused by Plasmodium falciparum‐infected
erythrocytes (IEs) that bind to chondroitin sulphate A (CSA) in the placenta by PAM …

Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants

L Barfod, T Dobrilovic, P Magistrado… - The Journal of …, 2010 - journals.aai.org
Acquired protection from Plasmodium falciparum placental malaria, a major cause of
maternal, fetal, and infant morbidity, is mediated by IgG specific for the P. falciparum …

[HTML][HTML] Characterization of anti-var2CSA-PfEMP1 cytoadhesion inhibitory mouse monoclonal antibodies

M Avril, B Gamain, C Lépolard, N Viaud, A Scherf… - Microbes and …, 2006 - Elsevier
Pregnancy-associated malaria (PAM) is associated with the massive sequestration of
erythrocytes infected with CSA-binding parasites in the placenta. Natural protective immunity …

[HTML][HTML] A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?

JYA Doritchamou, JP Renn, L Hviid, PE Duffy - PLoS Pathogens, 2023 - journals.plos.org
VAR2CSA is the Plasmodium falciparum variant surface antigen that mediates binding of
infected erythrocytes to chondroitin sulfate A (CSA) and their sequestration in intervillous …

[HTML][HTML] Differential Recognition of P. falciparum VAR2CSA Domains by Naturally Acquired Antibodies in Pregnant Women from a Malaria …

KJM Brolin, KEM Persson, M Wahlgren, SJ Rogerson… - PLoS …, 2010 - journals.plos.org
Background Plasmodium falciparum infected red blood cells (iRBC) express variant surface
antigens (VSA) of which VAR2CSA is involved in placental sequestration and causes …

Immunization with VAR2CSA-DBL5 Recombinant Protein Elicits Broadly Cross-Reactive Antibodies to Placental Plasmodium falciparum-Infected Erythrocytes

M Avril, MM Cartwright, MJ Hathaway… - Infection and …, 2010 - Am Soc Microbiol
Pregnancy-associated malaria is a severe clinical syndrome associated with the
sequestration of Plasmodium falciparum-infected erythrocytes in the placenta. Placental …

Identification of Plasmodium falciparum var1CSA and var2CSA domains that bind IgM natural antibodies

JP Semblat, A Raza, SA Kyes, JA Rowe - Molecular and biochemical …, 2006 - Elsevier
Malaria in pregnancy is responsible for maternal anaemia, low-birth-weight babies and
infant deaths. Plasmodium falciparum infected erythrocytes are thought to cause placental …

High Level of var2csa Transcription by Plasmodium falciparum Isolated from the Placenta

NG Tuikue Ndam, A Salanti, G Bertin… - The Journal of …, 2005 - academic.oup.com
Plasmodium falciparum parasites that bind to chondroitin sulphate A (CSA) express unique
variant surface antigens that are involved in the placental sequestration that precipitates …

[HTML][HTML] Strain-Transcendent Immune Response to Recombinant Var2CSA DBL5-ε Domain Block P. falciparum Adhesion to Placenta-Derived BeWo Cells under …

P Fernandez, S Petres, S Mecheri, J Gysin, A Scherf - PLoS One, 2010 - journals.plos.org
Background Pregnancy-associated malaria (PAM) is a serious consequence of the
adhesion to the placental receptor chondroitin sulfate A (CSA) of Plasmodium falciparum …

Antigenic Differences and Conservation among Placental Plasmodium falciparum–Infected Erythrocytes and Acquisition of Variant-Specific and Cross-Reactive …

JG Beeson, EJ Mann, TJ Byrne… - The Journal of …, 2006 - academic.oup.com
Background Pregnant women are infected by Plasmodium falciparum with novel antigenic
phenotypes that adhere to chondroitin sulfate A (CSA) and other receptors in the placenta …