Cations regulate membrane attachment and functionality of DNA nanostructures
D Morzy, R Rubio-Sánchez, H Joshi… - Journal of the …, 2021 - ACS Publications
The interplay between nucleic acids and lipids underpins several key processes in
molecular biology, synthetic biotechnology, vaccine technology, and nanomedicine. These …
molecular biology, synthetic biotechnology, vaccine technology, and nanomedicine. These …
[HTML][HTML] Interplay of the mechanical and structural properties of DNA nanostructures determines their electrostatic interactions with lipid membranes
D Morzy, C Tekin, V Caroprese, R Rubio-Sánchez… - Nanoscale, 2023 - pubs.rsc.org
Nucleic acids and lipids function in close proximity in biological processes, as well as in
nanoengineered constructs for therapeutic applications. As both molecules carry a rich …
nanoengineered constructs for therapeutic applications. As both molecules carry a rich …
DNA nanostructures interacting with lipid bilayer membranes
M Langecker, V Arnaut, J List… - Accounts of chemical …, 2014 - ACS Publications
Conspectus DNA has been previously shown to be useful as a material for the fabrication of
static nanoscale objects, and also for the realization of dynamic molecular devices and …
static nanoscale objects, and also for the realization of dynamic molecular devices and …
DNA nanostructures in vitro, in vivo and on membranes
Recent developments in DNA nanotechnology brought rich structural and functional
diversity. However, for DNA nanostructures to perform in a biologically relevant context …
diversity. However, for DNA nanostructures to perform in a biologically relevant context …
Dynamic interactions between lipid-tethered DNA and phospholipid membranes
Lipid-anchored DNA can attach functional cargo to bilayer membranes in DNA
nanotechnology, synthetic biology, and cell biology research. To optimize DNA anchoring …
nanotechnology, synthetic biology, and cell biology research. To optimize DNA anchoring …
Controlling aggregation of cholesterol-modified DNA nanostructures
DNA nanotechnology allows for the design of programmable DNA-built nanodevices which
controllably interact with biological membranes and even mimic the function of natural …
controllably interact with biological membranes and even mimic the function of natural …
[HTML][HTML] Emerging applications at the interface of DNA nanotechnology and cellular membranes: Perspectives from biology, engineering, and physics
DNA nanotechnology has proven exceptionally apt at probing and manipulating biological
environments as it can create nanostructures of almost arbitrary shape that permit countless …
environments as it can create nanostructures of almost arbitrary shape that permit countless …
Binding of DNA to zwitterionic lipid layers mediated by divalent cations
Divalent cations, ie, calcium, magnesium, and others, are able to enhance the ability of DNA
to interact with membranes that are composed of zwitterionic lipids such as …
to interact with membranes that are composed of zwitterionic lipids such as …
Molecular mechanism of calcium-induced adsorption of DNA on zwitterionic phospholipid membranes
AY Antipina, AA Gurtovenko - The Journal of Physical Chemistry …, 2015 - ACS Publications
Interaction of DNA with zwitterionic phospholipids is an important long-standing problem in
the field of liposome-based gene delivery. Although it is well-established that divalent …
the field of liposome-based gene delivery. Although it is well-established that divalent …
Polymorphism of DNA–anionic liposome complexes reveals hierarchy of ion-mediated interactions
Self-assembled DNA delivery systems based on anionic lipids (ALs) complexed with DNA
mediated by divalent cations have been recently introduced as an alternative to cationic lipid …
mediated by divalent cations have been recently introduced as an alternative to cationic lipid …