Tapering and discontinuation of systemic medications in psoriasis patients with low disease activity

L Shi, N Lian, L Liu, M Chen - Dermatologic Therapy, 2020 - Wiley Online Library
Psoriasis is a chronic disease and often requires long‐term treatment, especially in patients
with moderate‐to‐severe psoriasis. It remains controversial whether the doses of systemic …

A treatment strategy for psoriasis: transitioning from systemic therapy to biologic agents

A Ortiz, PS Yamauchi - SKINmed: Dermatology for the Clinician, 2006 - Wiley Online Library
Systemic agents such as methotrexate and cyclo‐sporine are commonly used in the
treatment of psoriasis. Long‐term continuous use is not recommended due to potential …

Patient-reported reasons for the discontinuation of commonly used treatments for moderate to severe psoriasis

H Yeung, J Wan, AS Van Voorhees, KC Duffin… - Journal of the American …, 2013 - Elsevier
BACKGROUND: Despite widespread dissatisfaction and low treatment persistence in
moderate to severe psoriasis, patients' reasons behind treatment discontinuation remain …

An evolution in switching therapy for psoriasis patients who fail to meet treatment goals

F Kerdel, M Zaiac - Dermatologic therapy, 2015 - Wiley Online Library
Switching psoriasis treatment is a common, accepted practice that is used to improve
disease management and improve patient outcomes (eg, when patients are experiencing …

Reasons for treatment changes in patients with moderate to severe psoriasis

KL Anderson, SR Feldman - Journal of Cutaneous Medicine …, 2015 - journals.sagepub.com
Background: Psoriasis treatment involves multiple treatment arms. Treatment choice
depends on many factors and may change, due to the chronicity of psoriasis. Objective: The …

Switching biologics in the treatment of psoriasis: a multicenter experience

E Özkur, İ Kıvanç Altunay, İ Oğuz Topal, S Aytekin… - Dermatology, 2021 - karger.com
Abstract Background/Objective: The purpose of our study was to provide evidence on the
treatment choices, reasons, and results of switching between biologic agents in treating …

Drug survival and predictor factors for discontinuation of methotrexate in psoriasis: a real‐life multicenter study

T Ozkok Akbulut, F Topaloglu Demir… - International Journal …, 2021 - Wiley Online Library
Background Drug survival is useful to evaluate long‐term drug performance in daily practice.
The aim of this study was to evaluate drug survival for methotrexate (MTX) monotherapy in …

Dose tapering of biologics in patients with psoriasis: a scoping review

CAJ Michielsens, ME Van Muijen, LM Verhoef… - Drugs, 2021 - Springer
Introduction Biologics serve as a cornerstone in psoriasis treatment, with low disease activity
or sometimes even clinical remission as a realistic treatment outcome. So far, it is unclear …

Methotrexate versus cyclosporine in moderate-to-severe chronic plaque psoriasis

VMR Heydendael, PI Spuls, BC Opmeer… - … England Journal of …, 2003 - Mass Medical Soc
Background Methotrexate and cyclosporine are well-known systemic therapies for moderate-
to-severe chronic plaque psoriasis. We conduced a randomized, controlled trial comparing …

Initiation, switching, and cessation of psoriasis treatments among patients with moderate to severe psoriasis in the United States

AW Armstrong, JW Koning, S Rowse, H Tan… - Clinical drug …, 2017 - Springer
Background Psoriasis patients frequently switch among multiple therapies while managing
their psoriasis. Determining treatment transitions is fundamental to understanding how …