Publisher Summary This chapter provides an update on pyridine and piperidine alkaloids.
Cardiovascular effects of nicotine and cotinine have been studied. One study reported an …

(+/-)-Ethylmethyl-1, 4-dihydro-2, 6-dimethyl-4-(3-nitrophenyl)-3, 5-pyridinedicarboxylate
(nitrendipine, Bay e 5009) 1, a calcium antagonistic 1, 4-dihydropyridine derivative, is …

111. Pyrido [l, 2-a] pyrimidine as a Carrie A. Monoamino Oxidase Inhibition B.
Antihypertensive Activity................................................. C. Insecticide Activity …

Publisher Summary This chapter focuses on pharmacologically active pyridazine
derivatives. This chapter describes that the cardiovascular diseases occupy first place as …

Di-and triaminopyrimidine 3-oxides (eg, 2, 4-diamino-6-piperidinylpyrimidine 3-oxide and 2,
4-diamino-6-(diallylammo) triazine 3-oxide) react with sources of sulfur trioxide, such as …

In vitro and in vivo modulation of drug metabolizing enzymes by piperine was investigated in
microsomes of rats and guinea pigs. In vitro piperine caused concentration related inhibition …

The effects of (−)-nicotine (0.0005–500 μM),(+)-nicotine (0.0005–50 μM) and (−)-cotinine
(0.0005–500 μM) on arachidonic acid metabolism were investigated in Ca2+ ionophore …

BACKGROUND It is unfortunate that the compounds collectively known as pyrrolizidine
alkaloids (PA) were not given a more euphonious name. Even chemists stumble over the …

The synthesis and antihypertensive activity of 4-(l, 2-dihydro-2-oxo-l-pyridyl)-2fi-l-
benzopyran-3-ols are described. The unsubstituted pyridone adduct lead compound 7e is …

This study was designed to determine the effectiveness of 5-(3-Hydroxybenzylidene)-2, 4, 6
(1H, 3H, 5H)-pyrimidinetrione (SR-5), 5-(4-Hydroxybenzylidene)-2, 4, 6 (1H, 3H, 5H) …