[HTML][HTML] Reducing cardiac injury during ST-elevation myocardial infarction: a reasoned approach to a multitarget therapeutic strategy

A Bellis, G Di Gioia, C Mauro, C Mancusi… - Journal of Clinical …, 2021 - mdpi.com
The significant reduction in 'ischemic time'through capillary diffusion of primary
percutaneous intervention (pPCI) has rendered myocardial-ischemia reperfusion injury …

Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations

DJ Hausenloy, HE Botker, T Engstrom… - European heart …, 2017 - academic.oup.com
Ischaemic heart disease (IHD) remains the leading cause of death and disability in Europe
and worldwide. A major cause of morbidity and mortality in IHD patients is an acute ST …

Improving myocardial injury, infarct size, and myocardial salvage in the era of primary PCI for STEMI

G Ndrepepa - Coronary Artery Disease, 2015 - journals.lww.com
ST-segment elevation myocardial infarction (STEMI) is a major cause of mortality and
disability worldwide. Reperfusion therapy by thrombolysis or primary percutaneous coronary …

Reperfusion in STEMI patients: still a role for cardioprotection?

F Ottani, U Limbruno, R Latini, L Misuraca… - Minerva …, 2018 - europepmc.org
Ischemic heart disease remains a leading cause of death worldwide, responsible for an
estimated 17.5 million deaths in 2012. Mortality from ST-elevation myocardial infarction …

Reducing myocardial infarct size: challenges and future opportunities

H Bulluck, DM Yellon, DJ Hausenloy - Heart, 2016 - heart.bmj.com
Despite prompt reperfusion by primary percutaneous coronary intervention (PPCI), the
mortality and morbidity of patients presenting with an acute ST-segment elevation …

Optimized treatment of ST-elevation myocardial infarction: the unmet need to target coronary microvascular obstruction as primary treatment goal to further improve …

G Niccoli, RA Montone, B Ibanez, H Thiele… - Circulation …, 2019 - Am Heart Assoc
Primary percutaneous coronary intervention is nowadays the preferred reperfusion strategy
for patients with acute ST-segment–elevation myocardial infarction, aiming at restoring …

Myocardial reperfusion injury: looking beyond primary PCI

GM Fröhlich, P Meier, SK White, DM Yellon… - European heart …, 2013 - academic.oup.com
Coronary heart disease (CHD) is the leading cause of death and disability in Europe. For
patients presenting with an acute ST-segment elevation myocardial infarction (STEMI) …

Reperfusion injury in ST-segment elevation myocardial infarction: the final frontier

G Ndrepepa, R Colleran, A Kastrati - Coronary Artery Disease, 2017 - journals.lww.com
ST-segment elevation myocardial infarction is a major cause of morbidity and mortality
worldwide. Reperfusion injury (RI) following the opening of an occluded coronary artery …

[HTML][HTML] Ischemia–reperfusion injury is still a big hurdle to overcome for treatment of acute myocardial infarction

T Inoue - Journal of Cardiology, 2016 - journal-of-cardiology.com
Since it has been elucidated that myocardial reperfusion can reduce myocardial infarct size
following an acute coronary artery occlusion, nowadays, myocardial reperfusion therapy …

[HTML][HTML] Treatment of myocardial ischaemia-reperfusion injury in patients with ST-segment elevation myocardial infarction: promise, disappointment, and hope

J He, NG Bellenger, AJ Ludman, AC Shore… - Reviews in …, 2022 - imrpress.com
Acute myocardial infarction (AMI) is a major cause of morbidity and mortality worldwide.
Timely reperfusion with primary percutaneous coronary intervention (PPCI) remains the gold …