Adipose tissue exhibits remarkable plasticity with capacity to change in size and cellular
composition under physiological and pathophysiological conditions. The emergence of …

The complex relationship between metabolic disease risk and body fat distribution in
humans involves cellular characteristics that are specific to body fat compartments. Here we …

Adipose tissues display a remarkable ability to adapt to the dietary status. Here, we have
applied single-nucleus RNA-seq to map the plasticity of mouse epididymal white adipose …

When normalized to volume, adipose tissue is comprised mainly of large lipid metabolizing
and storing cells called adipocytes. Strikingly, the numerical representation of non …

Adipose tissue depots in distinct anatomical locations mediate key aspects of metabolism,
including energy storage, nutrient release, and thermogenesis. Although adipocytes make …

Adipose tissue is an important regulator of whole-body metabolism and energy
homeostasis. The unprecedented growth of obesity and metabolic disease worldwide has …

The contribution of cellular heterogeneity and architecture to white adipose tissue (WAT)
function is poorly understood. Herein, we combined spatially resolved transcriptional …

A central function of adipose tissue is in the management of systemic energy homeostasis
that is achieved through the co-ordinated regulation of energy storage and mobilization …

Adipose tissue is a complex, multicellular organ that profoundly influences the function of
nearly all other organ systems through its diverse metabolite and adipokine secretome …

Understanding adipose tissue cellular heterogeneity and homeostasis is essential to
comprehend the cell type dynamics in metabolic diseases. Cellular subpopulations in the …